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RECOVERY OF A FILTRABLE VIRUS FROM CHILDREN WITH INFLUENZA

RECOVERY OF A FILTRABLE VIRUS FROM CHILDREN WITH INFLUENZA In the preceding paper1 Trask and I reported the recovery from children ill with diseases clinically indistinguishable from influenza of five strains of an agent which on inoculation into ferrets was capable of producing a febrile infection of the respiratory tract. The character of the reaction produced and some experimental studies made with the infectious agent will now be discussed. METHOD OF INOCULATING FERRETS All ferrets on their arrival at the laboratory were kept under observation for a minimum period of four days before being inoculated. During this time, daily temperature readings were taken in the morning, and the general normal behavior of the animals was observed. The temperature of the individual ferrets was found to fluctuate considerably, the normal limits lying usually between 38 and 40 C. (100.4 and 104 F.). On some occasions, newly arrived animals had nasal discharges and temperatures varying from 40 to 40.5 C. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American journal of diseases of children American Medical Association

RECOVERY OF A FILTRABLE VIRUS FROM CHILDREN WITH INFLUENZA

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Publisher
American Medical Association
Copyright
Copyright © 1936 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0096-8994
eISSN
1538-3628
DOI
10.1001/archpedi.1936.04140010087008
Publisher site
See Article on Publisher Site

Abstract

In the preceding paper1 Trask and I reported the recovery from children ill with diseases clinically indistinguishable from influenza of five strains of an agent which on inoculation into ferrets was capable of producing a febrile infection of the respiratory tract. The character of the reaction produced and some experimental studies made with the infectious agent will now be discussed. METHOD OF INOCULATING FERRETS All ferrets on their arrival at the laboratory were kept under observation for a minimum period of four days before being inoculated. During this time, daily temperature readings were taken in the morning, and the general normal behavior of the animals was observed. The temperature of the individual ferrets was found to fluctuate considerably, the normal limits lying usually between 38 and 40 C. (100.4 and 104 F.). On some occasions, newly arrived animals had nasal discharges and temperatures varying from 40 to 40.5 C.

Journal

American journal of diseases of childrenAmerican Medical Association

Published: Jul 1, 1936

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