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RECOVERY OF A FILTRABLE VIRUS FROM CHILDREN WITH INFLUENZA

RECOVERY OF A FILTRABLE VIRUS FROM CHILDREN WITH INFLUENZA During the continuation of an epidemiologic study1 of disease of the respiratory tract in children in the winter of 1934-1935, the ferret was included as an experimental animal. The use of this animal was suggested by Smith, Andrewes and Laidlaw2 and Francis,3 who demonstrated the susceptibility of the ferret to a filtrable virus recovered from persons with influenza. From the children of the group who were ill with what was apparently epidemic influenza, we obtained five strains of an agent which was capable of producing a febrile infection of the respiratory tract in ferrets, such as was described by the aforementioned workers. This agent was not recovered from persons suffering from other diseases included in the study. In this paper we wish to describe the clinical material and the methods used. In a subsequent section our studies on the results of the inoculation of ferrets with strains http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American journal of diseases of children American Medical Association

RECOVERY OF A FILTRABLE VIRUS FROM CHILDREN WITH INFLUENZA

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Publisher
American Medical Association
Copyright
Copyright © 1936 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0096-8994
eISSN
1538-3628
DOI
10.1001/archpedi.1936.04140010076007
Publisher site
See Article on Publisher Site

Abstract

During the continuation of an epidemiologic study1 of disease of the respiratory tract in children in the winter of 1934-1935, the ferret was included as an experimental animal. The use of this animal was suggested by Smith, Andrewes and Laidlaw2 and Francis,3 who demonstrated the susceptibility of the ferret to a filtrable virus recovered from persons with influenza. From the children of the group who were ill with what was apparently epidemic influenza, we obtained five strains of an agent which was capable of producing a febrile infection of the respiratory tract in ferrets, such as was described by the aforementioned workers. This agent was not recovered from persons suffering from other diseases included in the study. In this paper we wish to describe the clinical material and the methods used. In a subsequent section our studies on the results of the inoculation of ferrets with strains

Journal

American journal of diseases of childrenAmerican Medical Association

Published: Jul 1, 1936

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