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Recent Trends in the Prevalence of Coronary Disease

Recent Trends in the Prevalence of Coronary Disease ORIGINAL INVESTIGATION A Population-Based Autopsy Study of Nonnatural Deaths Peter N. Nemetz, PhD; Ve´ronique L. Roger, MD, MPH; Jeanine E. Ransom, BS; Kent R. Bailey, PhD; William D. Edwards, MD; Cynthia L. Leibson, PhD Background: Despite increases in obesity and diabetes Results: Over the full period (1981-2004), 8.2% of the mellitus, mortality caused by coronary disease contin- 425 individuals had high-grade disease, and 83% had evi- ues to decline. Recent trends in coronary disease preva- dence of any disease. Age- and sex-adjusted regression lence are unknown. analyses revealed temporal declines over the full period (1981-2004) for high-grade disease, any disease, and grade Methods: There were 3237 deaths among Olmsted of coronary disease. Declines in the grade of coronary dis- County, Minnesota, residents aged 16 through 64 years dur- ease ended after 1995 (P.01 for every artery) and pos- ing the 1981-2004 period. Of the 515 due to accident, sui- sibly reversed after 2000 (P=.06 for LCx). cide, homicide, or a manner that could not be deter- mined, 425 individuals (82%) had coronary anatomy Conclusions: Declines in coronary disease prevalence over- graded. Pathology reports were reviewed for the grade of all (during 1981-2004) reinforce arguments that any in- coronary disease http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Internal Medicine American Medical Association

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Publisher
American Medical Association
Copyright
Copyright 2008 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6106
eISSN
2168-6114
DOI
10.1001/archinternmed.2007.79
pmid
18268166
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL INVESTIGATION A Population-Based Autopsy Study of Nonnatural Deaths Peter N. Nemetz, PhD; Ve´ronique L. Roger, MD, MPH; Jeanine E. Ransom, BS; Kent R. Bailey, PhD; William D. Edwards, MD; Cynthia L. Leibson, PhD Background: Despite increases in obesity and diabetes Results: Over the full period (1981-2004), 8.2% of the mellitus, mortality caused by coronary disease contin- 425 individuals had high-grade disease, and 83% had evi- ues to decline. Recent trends in coronary disease preva- dence of any disease. Age- and sex-adjusted regression lence are unknown. analyses revealed temporal declines over the full period (1981-2004) for high-grade disease, any disease, and grade Methods: There were 3237 deaths among Olmsted of coronary disease. Declines in the grade of coronary dis- County, Minnesota, residents aged 16 through 64 years dur- ease ended after 1995 (P.01 for every artery) and pos- ing the 1981-2004 period. Of the 515 due to accident, sui- sibly reversed after 2000 (P=.06 for LCx). cide, homicide, or a manner that could not be deter- mined, 425 individuals (82%) had coronary anatomy Conclusions: Declines in coronary disease prevalence over- graded. Pathology reports were reviewed for the grade of all (during 1981-2004) reinforce arguments that any in- coronary disease

Journal

JAMA Internal MedicineAmerican Medical Association

Published: Feb 11, 2008

References