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Randomized Controlled Trial of Cognitive Behavioral Therapy vs Standard Treatment to Prevent Recurrent Cardiovascular Events in Patients With Coronary Heart Disease

Randomized Controlled Trial of Cognitive Behavioral Therapy vs Standard Treatment to Prevent... ORIGINAL INVESTIGATION Randomized Controlled Trial of Cognitive Behavioral Therapy vs Standard Treatment to Prevent Recurrent Cardiovascular Events in Patients With Coronary Heart Disease Secondary Prevention in Uppsala Primary Health Care Project (SUPRIM) Mats Gulliksson, MD, PhD; Gunilla Burell, PhD; Bengt Vessby, MD, PhD; Lennart Lundin, MD, PhD; Henrik Toss, MD, PhD; Kurt Svärdsudd, MD, PhD Background: Psychosocial factors are independently as- fatal first recurrent CVD events (hazard ratio [95% con- sociated with increased risk of cardiovascular disease (CVD) fidence interval], 0.59 [0.42-0.83]; P = .002), 45% fewer morbidity and mortality, but the effects of psychosocial fac- recurrent acute myocardial infarctions (0.55 [0.36-0.85]; tor intervention on CVD are uncertain. We performed a ran- P = .007), and a nonsignificant 28% lower all-cause mor- domized controlled clinical trial of cognitive behavioral tality (0.72 [0.40-1.30]; P = .28) than the reference group therapy (CBT) to measure its effects on CVD recurrence. after adjustment for other outcome-affecting variables. In the CBT group there was a strong dose-response effect Methods: The study included 362 women and men 75 between intervention group attendance and outcome. years or younger who were discharged from the hospi- During the first 2 years of follow-up, there were no sig- http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Internal Medicine American Medical Association

Randomized Controlled Trial of Cognitive Behavioral Therapy vs Standard Treatment to Prevent Recurrent Cardiovascular Events in Patients With Coronary Heart Disease

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References (34)

Publisher
American Medical Association
Copyright
Copyright 2011 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6106
eISSN
2168-6114
DOI
10.1001/archinternmed.2010.510
pmid
21263103
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL INVESTIGATION Randomized Controlled Trial of Cognitive Behavioral Therapy vs Standard Treatment to Prevent Recurrent Cardiovascular Events in Patients With Coronary Heart Disease Secondary Prevention in Uppsala Primary Health Care Project (SUPRIM) Mats Gulliksson, MD, PhD; Gunilla Burell, PhD; Bengt Vessby, MD, PhD; Lennart Lundin, MD, PhD; Henrik Toss, MD, PhD; Kurt Svärdsudd, MD, PhD Background: Psychosocial factors are independently as- fatal first recurrent CVD events (hazard ratio [95% con- sociated with increased risk of cardiovascular disease (CVD) fidence interval], 0.59 [0.42-0.83]; P = .002), 45% fewer morbidity and mortality, but the effects of psychosocial fac- recurrent acute myocardial infarctions (0.55 [0.36-0.85]; tor intervention on CVD are uncertain. We performed a ran- P = .007), and a nonsignificant 28% lower all-cause mor- domized controlled clinical trial of cognitive behavioral tality (0.72 [0.40-1.30]; P = .28) than the reference group therapy (CBT) to measure its effects on CVD recurrence. after adjustment for other outcome-affecting variables. In the CBT group there was a strong dose-response effect Methods: The study included 362 women and men 75 between intervention group attendance and outcome. years or younger who were discharged from the hospi- During the first 2 years of follow-up, there were no sig-

Journal

JAMA Internal Medicine – American Medical Association

Published: Jan 24, 2011

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