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Randomized Clinical Trial Progress to Inform Care for Out-of-Hospital Cardiac Arrest

Randomized Clinical Trial Progress to Inform Care for Out-of-Hospital Cardiac Arrest Opinion Editorials represent the opinions of the authors and JAMA EDITORIAL and not those of the American Medical Association. Randomized Clinical Trial Progress to Inform Care for Out-of-Hospital Cardiac Arrest Christopher B. Granger, MD; Lance B. Becker, MD Approximately300000patientsexperienceout-of-hospitalcar- cal trials of cardiac arrest, particularly in the out-of-hospital set- diac arrest per year in the United States, and less than 10% sur- ting, are enormously challenging, because of the need both to vive to hospital discharge. Regional heterogeneity in out- follow procedures involving authorization for waiver of in- comes, with a 5-fold greater formed consent and to conduct trials in the underresourced and likelihood of survival follow- fragmented environment of EMS. ing ventricular fibrillation It is in this context that the trial by Kim and colleagues is Related article page 45 arrest in Seattle, Washington, an important contribution. A total of 1359 patients, which is 7,8 than in counties in Alabama, has underscored the opportunity more than 3 times as many as in the prior trials combined, to improve care. National programs that define best practice with out-of-hospital cardiac arrest (583 with VF and 776 with- around community, emergency medical services (EMS), and out VF) were randomly assigned to http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Randomized Clinical Trial Progress to Inform Care for Out-of-Hospital Cardiac Arrest

JAMA , Volume 311 (1) – Jan 1, 2014

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Publisher
American Medical Association
Copyright
Copyright 2013 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2013.282174
pmid
24240668
Publisher site
See Article on Publisher Site

Abstract

Opinion Editorials represent the opinions of the authors and JAMA EDITORIAL and not those of the American Medical Association. Randomized Clinical Trial Progress to Inform Care for Out-of-Hospital Cardiac Arrest Christopher B. Granger, MD; Lance B. Becker, MD Approximately300000patientsexperienceout-of-hospitalcar- cal trials of cardiac arrest, particularly in the out-of-hospital set- diac arrest per year in the United States, and less than 10% sur- ting, are enormously challenging, because of the need both to vive to hospital discharge. Regional heterogeneity in out- follow procedures involving authorization for waiver of in- comes, with a 5-fold greater formed consent and to conduct trials in the underresourced and likelihood of survival follow- fragmented environment of EMS. ing ventricular fibrillation It is in this context that the trial by Kim and colleagues is Related article page 45 arrest in Seattle, Washington, an important contribution. A total of 1359 patients, which is 7,8 than in counties in Alabama, has underscored the opportunity more than 3 times as many as in the prior trials combined, to improve care. National programs that define best practice with out-of-hospital cardiac arrest (583 with VF and 776 with- around community, emergency medical services (EMS), and out VF) were randomly assigned to

Journal

JAMAAmerican Medical Association

Published: Jan 1, 2014

References