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Radiolabeled Antibody Therapy for Squamous Cell Carcinoma

Radiolabeled Antibody Therapy for Squamous Cell Carcinoma Abstract To the Editor.—By questioning the size of tumors on live mice pictured in the article by Shikani et al,1 Brown has provided an important contribution to the process of peer review. Brown's letter resulted in the promulgation of a new policy for the Archives to ensure that all studies on animals must affirm that the methods were performed in accordance with a protocol approved by the institutional animal care and use committee. In this particular case, the study had been approved by The Johns Hopkins (Baltimore, Md) committee; however, there was insufficient clarification of criteria for killing animals with large tumors. The resultant institutional review has raised the level of sensitivity to this issue among the investigators and the committee members. We are all grateful for Brown's vigilance and leadership. References 1. Shikani AH, Richtsmeier WJ, Klein JL, Kopher KA. Radiolabeled antibody therapy for squamous cell carcinoma of the head and neck . Arch Otolaryngol Head Neck Surg. 1992;118:521-525.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Otolaryngology - Head & Neck Surgery American Medical Association

Radiolabeled Antibody Therapy for Squamous Cell Carcinoma

Radiolabeled Antibody Therapy for Squamous Cell Carcinoma

Abstract

Abstract To the Editor.—By questioning the size of tumors on live mice pictured in the article by Shikani et al,1 Brown has provided an important contribution to the process of peer review. Brown's letter resulted in the promulgation of a new policy for the Archives to ensure that all studies on animals must affirm that the methods were performed in accordance with a protocol approved by the institutional animal care and use committee. In this particular case, the study had been...
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Publisher
American Medical Association
Copyright
Copyright © 1993 American Medical Association. All Rights Reserved.
ISSN
0886-4470
eISSN
1538-361X
DOI
10.1001/archotol.1993.01880190095023
Publisher site
See Article on Publisher Site

Abstract

Abstract To the Editor.—By questioning the size of tumors on live mice pictured in the article by Shikani et al,1 Brown has provided an important contribution to the process of peer review. Brown's letter resulted in the promulgation of a new policy for the Archives to ensure that all studies on animals must affirm that the methods were performed in accordance with a protocol approved by the institutional animal care and use committee. In this particular case, the study had been approved by The Johns Hopkins (Baltimore, Md) committee; however, there was insufficient clarification of criteria for killing animals with large tumors. The resultant institutional review has raised the level of sensitivity to this issue among the investigators and the committee members. We are all grateful for Brown's vigilance and leadership. References 1. Shikani AH, Richtsmeier WJ, Klein JL, Kopher KA. Radiolabeled antibody therapy for squamous cell carcinoma of the head and neck . Arch Otolaryngol Head Neck Surg. 1992;118:521-525.Crossref

Journal

Archives of Otolaryngology - Head & Neck SurgeryAmerican Medical Association

Published: Jul 1, 1993

References