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RADIOACTIVE IODINE IN THE STUDY OF THYROID PHYSIOLOGY

RADIOACTIVE IODINE IN THE STUDY OF THYROID PHYSIOLOGY In previously published experiments of this series1 radioactive iodine was used as an indicator in the study of animal and human thyroid physiology and iodine metabolism. Much of this preliminary work was done with a view to the discovery of the conditions under which radioactive iodine might be administered with maximum radiational effect in the pathologic thyroid of patients ill with hyperthyroidism. The present paper is a progress report on our early experiences (1941-1946) with such "internal irradiation" in the treatment of 29 cases of hyperthyroidism. It is, indeed, a three to five year follow-up report on these cases. PROCEDURE Patients were selected who had had no previous iodine treatment and who were judged clinically to have hyperthyroidism. The usual clinical tests were made and the patients were presented to the Thyroid Clinic of the Massachusetts General Hospital for discussion and determination of their suitability for this type of http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

RADIOACTIVE IODINE IN THE STUDY OF THYROID PHYSIOLOGY

JAMA , Volume 131 (2) – May 11, 1946

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References (5)

Publisher
American Medical Association
Copyright
Copyright © 1946 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1946.02870190005002
Publisher site
See Article on Publisher Site

Abstract

In previously published experiments of this series1 radioactive iodine was used as an indicator in the study of animal and human thyroid physiology and iodine metabolism. Much of this preliminary work was done with a view to the discovery of the conditions under which radioactive iodine might be administered with maximum radiational effect in the pathologic thyroid of patients ill with hyperthyroidism. The present paper is a progress report on our early experiences (1941-1946) with such "internal irradiation" in the treatment of 29 cases of hyperthyroidism. It is, indeed, a three to five year follow-up report on these cases. PROCEDURE Patients were selected who had had no previous iodine treatment and who were judged clinically to have hyperthyroidism. The usual clinical tests were made and the patients were presented to the Thyroid Clinic of the Massachusetts General Hospital for discussion and determination of their suitability for this type of

Journal

JAMAAmerican Medical Association

Published: May 11, 1946

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