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R1 Resection in Gastrointestinal Stromal Tumors Is Not Worse Than R0

R1 Resection in Gastrointestinal Stromal Tumors Is Not Worse Than R0 R1 Resection in Gastrointestinal Stromal Tumors Is Not Worse Than R0 Invited Commentary Invited Commentary Martin Almquist, MD; Erik Nordenström, MD Gastrointestinal stromal tumors (GISTs) are malignant tu- The authors found that, when excluding patients with tu- mors arising from interstitial cells of cajal that can be located mor rupture as defined previously, patients with microscopic in any part of the digestive system. Their most common sites R1 had no increased risk of recurrence or death than patients are the stomach and small with R0. Moreover, this was irrespective of treatment with TKI. intestine. Surgery either up- However, patients with tumor rupture had a significantly in- Related article front or after preoperative creased risk of recurrence and death. This challenges com- treatment with tyrosine ki- mon surgical wisdom that free surgical margins in oncologi- nase inhibitors (TKIs) is still the most important treatment mo- cal surgery are vital for patient outcomes but aligns with results 2 3 6 dality in GIST. In this issue of JAMA Surgery, Gronchi et al from the Oslo group. evaluate the association of microscopic radicality with patient Few patients in the study by Gronchi et al had GIST lo- outcomes. They use long-term data http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Surgery American Medical Association

R1 Resection in Gastrointestinal Stromal Tumors Is Not Worse Than R0

JAMA Surgery , Volume 155 (6) – Jun 1, 2020

R1 Resection in Gastrointestinal Stromal Tumors Is Not Worse Than R0

Abstract

R1 Resection in Gastrointestinal Stromal Tumors Is Not Worse Than R0 Invited Commentary Invited Commentary Martin Almquist, MD; Erik Nordenström, MD Gastrointestinal stromal tumors (GISTs) are malignant tu- The authors found that, when excluding patients with tu- mors arising from interstitial cells of cajal that can be located mor rupture as defined previously, patients with microscopic in any part of the digestive system. Their most common sites R1 had no increased risk of recurrence...
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Publisher
American Medical Association
Copyright
Copyright 2020 American Medical Association. All Rights Reserved.
ISSN
2168-6254
eISSN
2168-6262
DOI
10.1001/jamasurg.2020.0398
Publisher site
See Article on Publisher Site

Abstract

R1 Resection in Gastrointestinal Stromal Tumors Is Not Worse Than R0 Invited Commentary Invited Commentary Martin Almquist, MD; Erik Nordenström, MD Gastrointestinal stromal tumors (GISTs) are malignant tu- The authors found that, when excluding patients with tu- mors arising from interstitial cells of cajal that can be located mor rupture as defined previously, patients with microscopic in any part of the digestive system. Their most common sites R1 had no increased risk of recurrence or death than patients are the stomach and small with R0. Moreover, this was irrespective of treatment with TKI. intestine. Surgery either up- However, patients with tumor rupture had a significantly in- Related article front or after preoperative creased risk of recurrence and death. This challenges com- treatment with tyrosine ki- mon surgical wisdom that free surgical margins in oncologi- nase inhibitors (TKIs) is still the most important treatment mo- cal surgery are vital for patient outcomes but aligns with results 2 3 6 dality in GIST. In this issue of JAMA Surgery, Gronchi et al from the Oslo group. evaluate the association of microscopic radicality with patient Few patients in the study by Gronchi et al had GIST lo- outcomes. They use long-term data

Journal

JAMA SurgeryAmerican Medical Association

Published: Jun 1, 2020

References