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Quantitative Histologic Features of the Normal Frontal Sinus

Quantitative Histologic Features of the Normal Frontal Sinus Abstract • The entire mucosa from 30 normal frontal sinuses was removed, stained by the whole mount method, and the density of goblet cells and mucous glands was determined. There was an average of 6,300 goblet cells per square millimeter without statistically significant differences between the various walls. The glands were small and seromucous. In 87% of the sinuses, the gland density was less than 0.2 glands per square millimeter, and the total gland count did not exceed 40. This represents a totally negligible mucus production, which must be derived predominantly from the goblet cells. The density proved significantly higher in the inferior parts of the sinuses. The findings are discussed in relation to other areas of the respiratory tract. (Arch Otolaryngol 106:143-148, 1980) References 1. Zuckerkandl E: Normale und pathologische Anatomie der Nasenhöhle . Vienna, Braumüller, 1882, pp 133-134. 2. Schiefferdecker P: Histologie der Schleimhaut der Nase und ihrer Nebenhöhlen , in Heymann P: Handbuch der Laryngologie und Rhinologie . Vienna, Alfred Hölder, 1900, vol 3, pp 105-107. 3. Oppikofer E: Beiträge zur normalen und pathologischen Anatomie der Nase und ihrer Nebenhöhlen . Arch Laryngol Rhinol 19:28-80, 1907. 4. Brunner H: Nasal glands . Arch Otolaryngol 35:183-209, 1942.Crossref 5. Hajek M: Pathology and Treatment of the Inflammatory Diseases of the Nasal Accessory Sinuses . St Louis, CV Mosby Co, 1926, pp 78-80. 6. Hansel FK: Clinical and histopathologic studies of the nose and sinuses in allergy . J Allergy 1:43-70, 1930.Crossref 7. Semenov H: The pathology of the nose and paranasal sinuses in relation to allergy . Trans Am Acad Ophthalmol Otolaryngol 26:121-169, 1952. 8. Eggston AA, Wolff D: Histopathology of the Ear, Nose and Throat . Baltimore, Williams & Wilkins, 1947, pp 537-565. 9. Latta JS, Schall RF: The histology of the epithelium of the paranasal sinuses under various conditions . Ann Otol Rhinol Laryngol 43:945-959, 1934. 10. Tos M, Bak-Pedersen K: Density of goblet cells in chronic secretory otitis media: Findings in a biopsy material . Laryngoscope 85:377-383, 1975.Crossref 11. Ellefsen P, Tos M: Goblet cells in the human trachea: Quantitative studies of a pathological material . Arch Otolaryngol 95:547-555, 1972.Crossref 12. Tos M: Production of mucus in the middle ear and Eustachian tube . Ann Otol Rhinol Laryngol 83:44-58, 1974. 13. Tos M, Mogensen C: Nasal glands in nasal allergy . Acta Otolaryngol 83:498-504, 1977.Crossref 14. Messerklinger W: Über die Drainage der menschlichen Nasennebenhöhlen unter normalen und pathologischen Bedingungen . Monatsschr Ohrenheilk 101:313-326, 1967. 15. Messerklinger W: Ist in allen mensch lichen Stirnhöhlen das Prinzip des Sekrettransportes gleich? Arch Otorhinolaryngol 189:317-326, 1967. 16. Tos M: Mucous glands of the trachea in children: Quantitative studies . Anat Anz 126:146-160, 1970. 17. Tos M, Mogensen C: Mucous glands in nasal polyps . Arch Otolaryngol 103:407-413, 1977.Crossref 18. Bak-Pedersen K, Tos M: The mucous glands in chronic secretory otitis media . Acta Otolaryngol 72:14-27, 1971.Crossref 19. Mogensen C, Tos M: Quantitative histology of the maxillary sinus . Rhinology 55:129-140, 1977. 20. Mogensen C, Tos M: Density of goblet cells in the normal adult human nasal septum . Anat Anz 141:237-247, 1977. 21. Mogensen C, Tos M: Density of goblet cells on normal adult nasal turbinates . Anat Anz 142:322-330, 1977. 22. Tos M, Bak-Pedersen K: Goblet cell populations in the normal middle ear and Eustachian tube of children and adults . Ann Otol Rhinol Laryngol 85( (suppl 25) ):44-50, 1976. 23. Tos M, Mogensen C: Density of mucous glands in normal adult nasal turbinates . Arch Otorhinolaryngol 215:101-111, 1977.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Otolaryngology American Medical Association

Quantitative Histologic Features of the Normal Frontal Sinus

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Publisher
American Medical Association
Copyright
Copyright © 1980 American Medical Association. All Rights Reserved.
ISSN
0003-9977
DOI
10.1001/archotol.1980.00790270007002
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Abstract

Abstract • The entire mucosa from 30 normal frontal sinuses was removed, stained by the whole mount method, and the density of goblet cells and mucous glands was determined. There was an average of 6,300 goblet cells per square millimeter without statistically significant differences between the various walls. The glands were small and seromucous. In 87% of the sinuses, the gland density was less than 0.2 glands per square millimeter, and the total gland count did not exceed 40. This represents a totally negligible mucus production, which must be derived predominantly from the goblet cells. The density proved significantly higher in the inferior parts of the sinuses. The findings are discussed in relation to other areas of the respiratory tract. (Arch Otolaryngol 106:143-148, 1980) References 1. Zuckerkandl E: Normale und pathologische Anatomie der Nasenhöhle . Vienna, Braumüller, 1882, pp 133-134. 2. Schiefferdecker P: Histologie der Schleimhaut der Nase und ihrer Nebenhöhlen , in Heymann P: Handbuch der Laryngologie und Rhinologie . Vienna, Alfred Hölder, 1900, vol 3, pp 105-107. 3. Oppikofer E: Beiträge zur normalen und pathologischen Anatomie der Nase und ihrer Nebenhöhlen . Arch Laryngol Rhinol 19:28-80, 1907. 4. Brunner H: Nasal glands . Arch Otolaryngol 35:183-209, 1942.Crossref 5. Hajek M: Pathology and Treatment of the Inflammatory Diseases of the Nasal Accessory Sinuses . St Louis, CV Mosby Co, 1926, pp 78-80. 6. Hansel FK: Clinical and histopathologic studies of the nose and sinuses in allergy . J Allergy 1:43-70, 1930.Crossref 7. Semenov H: The pathology of the nose and paranasal sinuses in relation to allergy . Trans Am Acad Ophthalmol Otolaryngol 26:121-169, 1952. 8. Eggston AA, Wolff D: Histopathology of the Ear, Nose and Throat . Baltimore, Williams & Wilkins, 1947, pp 537-565. 9. Latta JS, Schall RF: The histology of the epithelium of the paranasal sinuses under various conditions . Ann Otol Rhinol Laryngol 43:945-959, 1934. 10. Tos M, Bak-Pedersen K: Density of goblet cells in chronic secretory otitis media: Findings in a biopsy material . Laryngoscope 85:377-383, 1975.Crossref 11. Ellefsen P, Tos M: Goblet cells in the human trachea: Quantitative studies of a pathological material . Arch Otolaryngol 95:547-555, 1972.Crossref 12. Tos M: Production of mucus in the middle ear and Eustachian tube . Ann Otol Rhinol Laryngol 83:44-58, 1974. 13. Tos M, Mogensen C: Nasal glands in nasal allergy . Acta Otolaryngol 83:498-504, 1977.Crossref 14. Messerklinger W: Über die Drainage der menschlichen Nasennebenhöhlen unter normalen und pathologischen Bedingungen . Monatsschr Ohrenheilk 101:313-326, 1967. 15. Messerklinger W: Ist in allen mensch lichen Stirnhöhlen das Prinzip des Sekrettransportes gleich? Arch Otorhinolaryngol 189:317-326, 1967. 16. Tos M: Mucous glands of the trachea in children: Quantitative studies . Anat Anz 126:146-160, 1970. 17. Tos M, Mogensen C: Mucous glands in nasal polyps . Arch Otolaryngol 103:407-413, 1977.Crossref 18. Bak-Pedersen K, Tos M: The mucous glands in chronic secretory otitis media . Acta Otolaryngol 72:14-27, 1971.Crossref 19. Mogensen C, Tos M: Quantitative histology of the maxillary sinus . Rhinology 55:129-140, 1977. 20. Mogensen C, Tos M: Density of goblet cells in the normal adult human nasal septum . Anat Anz 141:237-247, 1977. 21. Mogensen C, Tos M: Density of goblet cells on normal adult nasal turbinates . Anat Anz 142:322-330, 1977. 22. Tos M, Bak-Pedersen K: Goblet cell populations in the normal middle ear and Eustachian tube of children and adults . Ann Otol Rhinol Laryngol 85( (suppl 25) ):44-50, 1976. 23. Tos M, Mogensen C: Density of mucous glands in normal adult nasal turbinates . Arch Otorhinolaryngol 215:101-111, 1977.Crossref

Journal

Archives of OtolaryngologyAmerican Medical Association

Published: Mar 1, 1980

References