Abstract • Quantitative descriptors of corneal topography determined by computerized algorithm and designed to augment the information derived from topographic maps were evaluated in a clinical study. The surface regularity index, a measure of central corneal optical quality, was highly correlated with best spectacle-corrected visual acuity (p = 0.80, P<.001). The relatively low correlation between the surface asymmetry index, a measure of central corneal asymmetry, and best spectacle-corrected visual acuity (p = 0.62, P<.005) suggests that corneal symmetry is a lesser but still important determinant of the optical performance of the anterior corneal surface. There was also a high correlation between factors determined from computer-generated orthogonal simulated keratometer values and clinical keratometry values (mean corneal power, total corneal cylinder, and the location of the steepest corneal meridian). The information derived from these algorithms has both clinical and research applications and can be incorporated into computer-assisted topographic analysis systems. References 1. Klyce SD. Computer-assisted corneal topography: high resolution graphic presentation and analysis of keratoscopy . Invest Ophthalmol Vis Sci . 1984;25:1426-1435. 2. Maguire LJ, Singer DE, Klyce SD. Graphic presentation of computer analyzed keratoscope photographs . Arch Ophthalmol . 1987;94:223-230.Crossref 3. Gormley DJ, Gersten M, Koplin RS, Lubkin V. Corneal modeling . Cornea . 1988;7:30-35.Crossref 4. Cohen KL, Tripoli NK, Noecker RJ. Prospective analysis of photokeratoscopy for arcuate keratotomy to reduce postkeratoplasty astigmatism . Refract Corneal Surg . 1989;5:388-393. 5. Dingeldein SA, Klyce SD, Wilson SE. Quantitative descriptors of corneal shape derived from computer-assisted analysis of photokeratographs . Refract Corneal Surg . 1989;5:372-378. 6. Klyce SD, Wilson SE, Pittman SD, Wang J. Estimation of potential visual acuity from corneal shape . Invest Ophthalmol Vis Sci . 1989;30 ( (suppl) ):218. 7. Ferris FL, Kassoff A, Brenick GH, Bailey I. New visual acuity charts for clinical research . Am J Ophthalmol . 1982;94:91-96. 8. Wilson SE, Wang J, Klyce SD. Quantification and mathematical analysis of photokeratoscope images. In: Schanzlin DJ, Robin J, eds. Corneal Topography. New York, NY: Springer-Verlag NY Inc. In press. 9. Klyce SD, Wilson SE. Methods of analysis of corneal topography . Refract Corneal Surg . 1989;5:368-371. 10. Dabezies OH, Holladay JT. Measurement of corneal curvature: keratometer (ophthalmometer) . In: Dabezies OH Jr, Cavanagh HD, Farris RL, Lemp MA, eds. Contact Lenses: The CLAO Guide to Basic Science and Clinical Practice . New York, NY: Grune & Stratton; 1986;17.1-17.29. 11. Dingeldein SA, Klyce SD. The topography of normal corneas . Am J Ophthalmol . 1989;107:512-518. 12. Maguire LJ, Bourne WM. Corneal topography of early keratoconus . Am J Ophthalmol . 1989;108:107-112. 13. Wilson SE, Lin DTC, Klyce SD. The topography of keratoconus . Cornea . 1991;10:2-8.Crossref 14. Rabinowitz YS, McDonnell PJ. Computer-assisted corneal topography in keratoconus . Refract Corneal Surg . 1989;5:400-408. 15. Wilson SE, Lin DTC, Klyce SD, Reidy JJ, Insler MS. Topographic changes in contact lens-induced warpage . Ophthalmology . 1990;97:734-744.Crossref 16. Dingeldein SA, Pittman SD, Wang J, Klyce SD. Analysis of corneal topographic data . Invest Ophthalmol Vis Sci . 1988;29( (suppl) ):389.
Archives of Ophthalmology – American Medical Association
Published: Mar 1, 1991
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