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Research Original Investigation Short-term Efficacy and Safety of Topical β-Blockers in Acute Migraine 21. Janakiraman RK, Ramasamy C. Pre-clinical 22. Gilmore B, Michael M. Treatment of acute 23. Mayans L, Walling A. Acute migraine headache: studies of timolol maleate matrix tablet formulated migraine headache. Am Fam Physician. 2011;83(3): treatment strategies. Am Fam Physician. 2018;97 with different polymers and ratios. Asian J Res Biol 271-280. (4):243-251. Pharm Sci. 2014;2(1):38-55. Accessed August 24, 2020. https://docisolation.prod.fire.glass/?guid= 9df27275-4fc9-4187-7614-2855499af36a Invited Commentary Bradley J. Katz, MD, PhD Migraine is the most common, chronic, serious neurologic con- the drops and recorded their headaches in a diary. At the conclu- sion of the trial, the 50 patients had recorded a total of 619 dition worldwide, affecting more than 11% of the world’s population. In the United States, it affects approximately 16% migraine attacks. Just under half of the attacks were treated with of women and 6% of men. Although migraine is a neurologic timolol, and just under half of the attacks were treated with illness, it is associated with a the placebo. The authors report that 233 timolol-treated attacks number of ocular and visual (82%) were associated with a clinically significant reduction in Related article page 1160
JAMA Ophthalmology – American Medical Association
Published: Nov 1, 2020
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