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PULMONARY EDEMA PRODUCED BY INTRATRACHEAL INJECTION OF MILK, FEEDING MIXTURES, AND SUGARS

PULMONARY EDEMA PRODUCED BY INTRATRACHEAL INJECTION OF MILK, FEEDING MIXTURES, AND SUGARS DURING the course of a study of experimental milk-aspiration pneumonia produced in rabbits by intratracheal injection of human milk, cow's milk, and feeding mixtures,1 it was found that injection of 10 to 20 cc. of the feeding mixtures often caused fatal pulmonary edema within a few minutes. Injections of similar amounts of human or cow's milk rarely produced this effect. Evaluation of the contents of the feeding mixture suggested that the difference in the effects of the injection of the feeding mixture as compared to injection of unfortified human milk or cow's milk was due to the larger amount of carbohydrate in the feeding mixture. This led to a more detailed study of the production of acute pulmonary edema by intratracheal injection of feeding mixtures, human milk, cow's milk, and solutions of the carbohydrates present in milk and the common feeding mixtures. METHODS Intratracheal injections of feeding mixture (2 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American journal of diseases of children American Medical Association

PULMONARY EDEMA PRODUCED BY INTRATRACHEAL INJECTION OF MILK, FEEDING MIXTURES, AND SUGARS

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Publisher
American Medical Association
Copyright
Copyright © 1953 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0096-8994
eISSN
1538-3628
DOI
10.1001/archpedi.1953.02050080052005
Publisher site
See Article on Publisher Site

Abstract

DURING the course of a study of experimental milk-aspiration pneumonia produced in rabbits by intratracheal injection of human milk, cow's milk, and feeding mixtures,1 it was found that injection of 10 to 20 cc. of the feeding mixtures often caused fatal pulmonary edema within a few minutes. Injections of similar amounts of human or cow's milk rarely produced this effect. Evaluation of the contents of the feeding mixture suggested that the difference in the effects of the injection of the feeding mixture as compared to injection of unfortified human milk or cow's milk was due to the larger amount of carbohydrate in the feeding mixture. This led to a more detailed study of the production of acute pulmonary edema by intratracheal injection of feeding mixtures, human milk, cow's milk, and solutions of the carbohydrates present in milk and the common feeding mixtures. METHODS Intratracheal injections of feeding mixture (2

Journal

American journal of diseases of childrenAmerican Medical Association

Published: Jul 1, 1953

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