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- Publisher
- American Medical Association
- Copyright
- Copyright © 1936 American Medical Association. All Rights Reserved.
- ISSN
- 0096-6754
- DOI
- 10.1001/archneurpsyc.1936.02260060162013
- Publisher site
- See Article on Publisher Site
Abstract
Abstract The clinical picture of puerperal eclampsia undoubtedly suggests a severe toxic state. Such a view is amply confirmed by the histologic observations of the condition of the visceral organs—the liver and especially the kidneys. Reports of detailed histopathologic studies of the central nervous system are scarce. As Dr. R. H. Jaffé gave me the opportunity to make a study of five cases of puerperal eclampsia, I am reporting here briefly the results of my observations on the changes in the central nervous system. REPORT OF CASES Case 1. —Multipara; eclampsia in labor; death seven hours after delivery. Edema and rarefaction of the brain; degenerative changes of ganglion cells; progressive (proliferative) reaction of the glia, blood vessels and meninges; increase in the microglia; glial nodule in medulla with mild perivascular infiltration. History. —A white woman aged 33 was admitted to the Cook County Hospital on June 15, 1933, in a stuporous References 1. Schmorl, W.: Zur Lehre von der Eklampsie , Arch. f. Gynäk. 65: 504, 1902.Crossref 2. Jaffé, Rudolph: Beitrag zur Frage der apoplektischen Blutung (an Hand eines Falles von Eklampsie) , Zentralbl. f. Gynäk. 51: 1387, 1927. 3. Baird, D., and Dunn, J. S.: Renal Lesions in Eclampsia and Nephritis of Pregnancy , J. Path. & Bact. 37:291, 1933. 4. Ayer, J. B.: Pathological Study of Experimental Meningitis , New York, Monograph 12, Rockefeller Institute for Medical Research, 1912, p. 36. 5. Hassin, George B.: Histopathology of the Peripheral and Central Nervous Systems , Baltimore, William Wood & Company, 1933. 6. Spielmeyer, W.: Kreislaufstörungen und Psychosen , Ztschr. f. d. ges. Neurol. u. Psychiat. 123:536, 1930 7. The Anatomic Substratum of the Convulsive State , Arch. Neurol. & Psychiat. 23:869 ( (May) ) 1930. 8. von Braunmühl, A.: Ueber Gehirnbefunde bei schweren Erregungszuständen , Ztschr. f. d. ges. Neurol. & Psychiat. 117:163, 1928 9. Ueber Gehirnveränderungen bei puerperaler Eklampsie und ihre Entstehung durch Kreislaufstörungen , von Braunmühl Ztschr. f. d. ges. Neurol. & Psychiat. 117:698, 1928. 10. Benoit, W.: Ein Beitrag zur Kenntnis der Rindenveränderungen bei Wochenbettseklampsie , Ztschr. f. d. ges. Neurol. u. Psychiat. 131:602, 1931. 11. Hechst, Bela: Ueber Gehirnbefunde bei urämischen Zuständen , Ztschr. f d. ges. Neurol. u. Psychiat. 139:544, 1932. 12. Bodechtel, G.: Hirnveränderungen bei den verschiedenen Formen der Urämie unter Berücksichtigung ihrer Pathogenese , Deutsches Arch. f. klin. Med. 174:541, 1933. 13. Williams, W.: Obstetrics , ed. 6, New York, D. Appleton & Co., 1930. 14. Goodall, J. R.: Toxemia of Pregnancy , J. A. M. A. 105:2121 ( (Dec. 28) ) 1935. 15. Hofbauer, J.: Die Aetiologie der Eklampsie , Zentralbl.f. Gynäk. 42:745, 1918. 16. Fauvet, E.: Die Eklampsie, eine hypophysäre Erkrankung , Arch. f. Gynäk. 155:100, 1933. 17. Anselmino, K. J.; Hoffman, F., and Kennedy, W. P.: The Relation of Hyperfunction of the Posterior Lobe of the Hypophysis to Eclampsia and Nephropathy of Pregnancy , Edinburgh M. J. 39:376, 1932. 18. Volhard, F., in Mohr, L., and Staehelin, R.: Handbuch der inneren Medizin , Berlin, Julius Springer, 1931, vol. 6, pt. 1. 19. Bell, E. T.: Renal Lesions in the Toxemias of Pregnancy , Am. J. Path. 6: 1, 1932. 20. Ricker, G.: Sklerose und Hypertonie der innervierten Arterien , Berlin, Julius Springer, 1927.
Journal
Archives of Neurology & Psychiatry – American Medical Association
Published: Jun 1, 1936
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