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Psychosis, Polydipsia, and Water Intoxication: Report of a Fatal Case

Psychosis, Polydipsia, and Water Intoxication: Report of a Fatal Case Abstract In the absence of complicating medical illness, psychogenic polydipsia has been regarded as a fairly benign process. This paper reports on a case of rapidly fatal water intoxication secondary to psychogenic polydipsia in a psychotic woman. A review of the literature revealed a strong association between psychosis and water intoxication in compulsive water drinkers. The possible role of neuroendocrine changes in psychosis is discussed and the danger of thiazide diuretics in psychogenic polydipsia is emphasized. References 1. Helwig FC, Schutz CB, Curry DE: Water intoxication: Report of a fatal human case with clinical, pathological, and experimental studies . JAMA 104:1569-1575, 1935.Crossref 2. Rowntree LG: Water intoxication . Arch Intern Med 32:157, 1923.Crossref 3. Water intoxication , lead article. Lancet 264:425-426, 1953. 4. Thorn NA: Antidiuretic hormone synthesis, release, and action under normal and pathological circumstances . Adv Metab Disord 4:39-73, 1970. 5. Walker GW, Whelton A: Water metabolism , in Harvey AM, et al (eds): The Principles and Practice of Medicine . New York, Appleton-Century-Crofts Inc, 1972, p 67. 6. Barlow ED, DeWardener HE: Compulsive water drinking . Q J Med 28:235-258, 1959. 7. Habener JF, Dashe AM, Solomon DH: Response of normal subjects to prolonged high fluid intake . J Appl Physiol 19:134-136, 1964. 8. Hobson JA, English JT: Self induced water intoxication . Ann Intern Med 58:324-332, 1963.Crossref 9. Beresford HR: Polydipsia, hydrochlorothiazide, and water intoxication . JAMA 214:879-883, 1970.Crossref 10. Carter TJ: Water intoxication . Br Med J 2:367, 1959.Crossref 11. Langgard H, Smith WD: Self-induced water intoxication without predisposing illness . N Engl J Med 266:378-381, 1966.Crossref 12. Ehrentheil OF, Marchand WE (eds): Clinical Medicine and the Psychotic Patient . Springfield, Ill, Charles C Thomas Publisher, 1960, p 82. 13. Resnick ME, Patterson C: Coma and convulsions due to compulsive water drinking . Neurology 19:1125-1126, 1969.Crossref 14. Murphy FJ, Zelman S: Water metabolism and the Psychiatric patient . J Urol 92:60-63, 1964. 15. Kennedy RM, Earley LE: Profound hyponatremia resulting from a thiazide-induced decrease in urinary diluting capacity in a patient with primary polydipsia . N Engl J Med 282:1185-1186, 1970.Crossref 16. Devereaux MW, McCormick RA: Psychogenic water intoxication: A case report . Am J Psychiatry 129:628-630, 1972. 17. Wynn V, Rob CG: Water intoxication: Differential diagnosis of hypotonic syndromes . Lancet 1:587-594, 1954.Crossref 18. Plum F, Posner JB: Diagnosis of Stupor and Coma . Philadelphia, FA Davis Co, 1966. 19. Wasterlain CG, Posner JB: Cerebral edema in water intoxication . Arch Neurol 19:71-78, 1968.Crossref 20. Fuisz RE: Hyponatremia . Medicine 38:149-170, 1963.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of General Psychiatry American Medical Association

Psychosis, Polydipsia, and Water Intoxication: Report of a Fatal Case

Archives of General Psychiatry , Volume 30 (1) – Jan 1, 1974

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Publisher
American Medical Association
Copyright
Copyright © 1974 American Medical Association. All Rights Reserved.
ISSN
0003-990X
eISSN
1598-3636
DOI
10.1001/archpsyc.1974.01760070090014
Publisher site
See Article on Publisher Site

Abstract

Abstract In the absence of complicating medical illness, psychogenic polydipsia has been regarded as a fairly benign process. This paper reports on a case of rapidly fatal water intoxication secondary to psychogenic polydipsia in a psychotic woman. A review of the literature revealed a strong association between psychosis and water intoxication in compulsive water drinkers. The possible role of neuroendocrine changes in psychosis is discussed and the danger of thiazide diuretics in psychogenic polydipsia is emphasized. References 1. Helwig FC, Schutz CB, Curry DE: Water intoxication: Report of a fatal human case with clinical, pathological, and experimental studies . JAMA 104:1569-1575, 1935.Crossref 2. Rowntree LG: Water intoxication . Arch Intern Med 32:157, 1923.Crossref 3. Water intoxication , lead article. Lancet 264:425-426, 1953. 4. Thorn NA: Antidiuretic hormone synthesis, release, and action under normal and pathological circumstances . Adv Metab Disord 4:39-73, 1970. 5. Walker GW, Whelton A: Water metabolism , in Harvey AM, et al (eds): The Principles and Practice of Medicine . New York, Appleton-Century-Crofts Inc, 1972, p 67. 6. Barlow ED, DeWardener HE: Compulsive water drinking . Q J Med 28:235-258, 1959. 7. Habener JF, Dashe AM, Solomon DH: Response of normal subjects to prolonged high fluid intake . J Appl Physiol 19:134-136, 1964. 8. Hobson JA, English JT: Self induced water intoxication . Ann Intern Med 58:324-332, 1963.Crossref 9. Beresford HR: Polydipsia, hydrochlorothiazide, and water intoxication . JAMA 214:879-883, 1970.Crossref 10. Carter TJ: Water intoxication . Br Med J 2:367, 1959.Crossref 11. Langgard H, Smith WD: Self-induced water intoxication without predisposing illness . N Engl J Med 266:378-381, 1966.Crossref 12. Ehrentheil OF, Marchand WE (eds): Clinical Medicine and the Psychotic Patient . Springfield, Ill, Charles C Thomas Publisher, 1960, p 82. 13. Resnick ME, Patterson C: Coma and convulsions due to compulsive water drinking . Neurology 19:1125-1126, 1969.Crossref 14. Murphy FJ, Zelman S: Water metabolism and the Psychiatric patient . J Urol 92:60-63, 1964. 15. Kennedy RM, Earley LE: Profound hyponatremia resulting from a thiazide-induced decrease in urinary diluting capacity in a patient with primary polydipsia . N Engl J Med 282:1185-1186, 1970.Crossref 16. Devereaux MW, McCormick RA: Psychogenic water intoxication: A case report . Am J Psychiatry 129:628-630, 1972. 17. Wynn V, Rob CG: Water intoxication: Differential diagnosis of hypotonic syndromes . Lancet 1:587-594, 1954.Crossref 18. Plum F, Posner JB: Diagnosis of Stupor and Coma . Philadelphia, FA Davis Co, 1966. 19. Wasterlain CG, Posner JB: Cerebral edema in water intoxication . Arch Neurol 19:71-78, 1968.Crossref 20. Fuisz RE: Hyponatremia . Medicine 38:149-170, 1963.Crossref

Journal

Archives of General PsychiatryAmerican Medical Association

Published: Jan 1, 1974

References