Psilocybin-Assisted Supportive Psychotherapy in the Treatment of Major Depression—Quo Vadis?

Psilocybin-Assisted Supportive Psychotherapy in the Treatment of Major Depression—Quo Vadis? Opinion EDITORIAL Psilocybin-Assisted Supportive Psychotherapy in the Treatment of Major Depression—Quo Vadis? Charles F. Reynolds III, MD In this issue of JAMA Psychiatry, Davis and colleagues at Take a step back for a moment and recall the etymology the Johns Hopkins Center for Psychedelic and Conscious- of psychedelic, a term derived from 2 Greek words, psyche (meaning soul, spirit, or mind) and delos (meaning clear or ness Research have contributed a timely and important proof-of-concept randomized clinical trial on the effects of manifest). With respect to the metaphors that we live by, the psilocybin-assisted support- psychedelic experience has been analogized to a psychologi- ive psychotherapy for the cal journey, which in the current treatment model is a jour- Related article treatment of major depres- ney accompanied by a therapist or guide who helps partici- sion. The authors reported rapid relief of depressive pants understand the challenges of the psychedelic experience, symptoms and high rates of response and remission that including issues and insights that might need further psycho- were sustained for more than 4 weeks in a sample of 24 logical integration (and by implication, to sustain antidepres- midlife adults, many of whom had chronic depression. The sant response http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Psychiatry American Medical Association

Psilocybin-Assisted Supportive Psychotherapy in the Treatment of Major Depression—Quo Vadis?

JAMA Psychiatry, Volume 78 (2) – Feb 4, 2021

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Publisher
American Medical Association
Copyright
Copyright 2020 American Medical Association. All Rights Reserved.
ISSN
2168-622X
eISSN
2168-6238
DOI
10.1001/jamapsychiatry.2020.2901
Publisher site
See Article on Publisher Site

Abstract

Opinion EDITORIAL Psilocybin-Assisted Supportive Psychotherapy in the Treatment of Major Depression—Quo Vadis? Charles F. Reynolds III, MD In this issue of JAMA Psychiatry, Davis and colleagues at Take a step back for a moment and recall the etymology the Johns Hopkins Center for Psychedelic and Conscious- of psychedelic, a term derived from 2 Greek words, psyche (meaning soul, spirit, or mind) and delos (meaning clear or ness Research have contributed a timely and important proof-of-concept randomized clinical trial on the effects of manifest). With respect to the metaphors that we live by, the psilocybin-assisted support- psychedelic experience has been analogized to a psychologi- ive psychotherapy for the cal journey, which in the current treatment model is a jour- Related article treatment of major depres- ney accompanied by a therapist or guide who helps partici- sion. The authors reported rapid relief of depressive pants understand the challenges of the psychedelic experience, symptoms and high rates of response and remission that including issues and insights that might need further psycho- were sustained for more than 4 weeks in a sample of 24 logical integration (and by implication, to sustain antidepres- midlife adults, many of whom had chronic depression. The sant response

Journal

JAMA PsychiatryAmerican Medical Association

Published: Feb 4, 2021

References

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