Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You and Your Team.

Learn More →

'Prune Belly' Syndrome-Reply

'Prune Belly' Syndrome-Reply Abstract In Reply.—The thoughts of Drs Kroovand and Perlmutter express the predominant opinion of the past relative to the pathogenesis of the "prune belly" syndrome. Our hypothesis, that the most common pathogenesis is early urethral obstruction, will be published in detail in the near future.1 Severe early urethral obstruction results in a host of secondary biomechanical deformations as a consequence of the back pressure. The problem in bladder and urethral musculature and its partial replacement by collagen is the result of the distensile pressure. The same is true for the variable impact of gross bladder distension on abdominal musculature. These deductions are made possible by the evaluation of embryos and fetuses who had severe urethral obstruction that was lethal in fetal life, which would seem to be the most common outcome. To survive to be born and be evaluated by the urologist, the individual with severe urethral obstruction must References 1. Pagon RA, Smith DW, Shepard TH: Urethral obstruction malformation complex: The most common cause for abdominal muscle deficiency and the "prune belly syndrome." J Pediatr , to be published. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Diseases of Children American Medical Association

'Prune Belly' Syndrome-Reply

Abstract

Abstract In Reply.—The thoughts of Drs Kroovand and Perlmutter express the predominant opinion of the past relative to the pathogenesis of the "prune belly" syndrome. Our hypothesis, that the most common pathogenesis is early urethral obstruction, will be published in detail in the near future.1 Severe early urethral obstruction results in a host of secondary biomechanical deformations as a consequence of the back pressure. The problem in bladder and urethral musculature and...
Loading next page...
 
/lp/american-medical-association/prune-belly-syndrome-reply-R70p4I6jdJ
Publisher
American Medical Association
Copyright
Copyright © 1979 American Medical Association. All Rights Reserved.
ISSN
0002-922X
DOI
10.1001/archpedi.1979.02130060098032
Publisher site
See Article on Publisher Site

Abstract

Abstract In Reply.—The thoughts of Drs Kroovand and Perlmutter express the predominant opinion of the past relative to the pathogenesis of the "prune belly" syndrome. Our hypothesis, that the most common pathogenesis is early urethral obstruction, will be published in detail in the near future.1 Severe early urethral obstruction results in a host of secondary biomechanical deformations as a consequence of the back pressure. The problem in bladder and urethral musculature and its partial replacement by collagen is the result of the distensile pressure. The same is true for the variable impact of gross bladder distension on abdominal musculature. These deductions are made possible by the evaluation of embryos and fetuses who had severe urethral obstruction that was lethal in fetal life, which would seem to be the most common outcome. To survive to be born and be evaluated by the urologist, the individual with severe urethral obstruction must References 1. Pagon RA, Smith DW, Shepard TH: Urethral obstruction malformation complex: The most common cause for abdominal muscle deficiency and the "prune belly syndrome." J Pediatr , to be published.

Journal

American Journal of Diseases of ChildrenAmerican Medical Association

Published: Jun 1, 1979

References