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References (40)
-
Amanda O’Reilly, R. Currie, David Clarke, David Clarke (2010)
HspB1 (Hsp 27) Expression and Neuroprotection in the RetinaMolecular Neurobiology, 42
-
A. Kanamori, Makoto Nakamura, H. Mukuno, Hidetaka Maeda, A. Negi (2004)
Diabetes has an additive effect on neural apoptosis in rat retina with chronically elevated intraocular pressureCurrent Eye Research, 28
-
A. Ebneter, R. Casson, J. Wood, G. Chidlow (2010)
Microglial activation in the visual pathway in experimental glaucoma: spatiotemporal characterization and correlation with axonal injury.Investigative ophthalmology & visual science, 51 12
-
G. Kalesnykas, M. Niittykoski, J. Rantala, R. Miettinen, A. Salminen, K. Kaarniranta, H. Uusitalo (2007)
The expression of heat shock protein 27 in retinal ganglion and glial cells in a rat glaucoma modelNeuroscience, 150
-
L. Zhong, John Bradley, W. Schubert, E. Ahmed, A. Adamis, D. Shima, G. Robinson, Y. Ng (2007)
Erythropoietin promotes survival of retinal ganglion cells in DBA/2J glaucoma mice.Investigative ophthalmology & visual science, 48 3
-
J. Tielsch, J. Katz, H. Quigley, J. Javitt, A. Sommer (1995)
Diabetes, intraocular pressure, and primary open-angle glaucoma in the Baltimore Eye Survey.Ophthalmology, 102 1
-
H. Kahn, H. Leibowitz, J. Ganley, M. Kini, T. Colton, Rita Nickerson, T. Dawber (1977)
The Framingham Eye Study. II. Association of ophthalmic pathology with single variables previously measured in the Framingham Heart Study.American journal of epidemiology, 106 1
-
R. Fechtner, N. Karunaratne, A. Khoury, T. Realini, Jianming Ren, M. Robison, George Shafranov, Gilbert Sussman, Mike Willman, Thomas Uihlein, E. Hartmann, Anna Norris, Melissa Perez, M. Piccone, Anna Singh, A. Gray (2002)
The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma.Archives of ophthalmology, 120 6
-
R. Casson, J. Wood, Neville Osborne (2004)
Hypoglycaemia exacerbates ischaemic retinal injury in ratsBritish Journal of Ophthalmology, 88
-
D. Castro, T. Prata, V. Lima, L. Biteli, C. Moraes, A. Paranhos (2009)
Corneal Viscoelasticity Differences Between Diabetic and Nondiabetic Glaucomatous PatientsJournal of Glaucoma, 19
-
J. Flammer, S. Orgül, V. Costa, N. Orzalesi, G. Krieglstein, L. Serra, J. Renard, E. Stefánsson (2002)
The impact of ocular blood flow in glaucomaProgress in Retinal and Eye Research, 21
-
D. Tomlinson, N. Gardiner (2008)
Glucose neurotoxicityNature Reviews Neuroscience, 9
-
G. Chidlow, M. Holman, J. Wood, R. Casson (2010)
Spatiotemporal characterization of optic nerve degeneration after chronic hypoperfusion in the rat.Investigative ophthalmology & visual science, 51 3
-
Neville Osborne, G. Chidlow, Christopher Layton, J. Wood, Robert Casson, José Melena (2004)
Optic nerve and neuroprotection strategiesEye, 18
-
F. Medeiros, R. Weinreb, P. Sample, C. Gomi, C. Bowd, J. Crowston, L. Zangwill (2005)
Validation of a predictive model to estimate the risk of conversion from ocular hypertension to glaucoma.Archives of ophthalmology, 123 10
-
C. Burgoyne, J. Morrison (2001)
The anatomy and pathophysiology of the optic nerve head in glaucoma.Journal of glaucoma, 10 5 Suppl 1
-
D. Meller, U. Eysel, R. Schmidt-Kastner (1994)
Transient immunohistochemical labelling of rat retinal axons during Wallerian degeneration by a monoclonal antibody to neurofilamentsBrain Research, 648
-
M. Pease, D. Zack, C. Berlinicke, K. Bloom, Frances Cone, Yuxia Wang, R. Klein, W. Hauswirth, H. Quigley (2009)
Effect of CNTF on retinal ganglion cell survival in experimental glaucoma.Investigative ophthalmology & visual science, 50 5
-
V. Chopra, R. Varma, B. Francis, Joanne Wu, M. Torres, S. Azen (2008)
Type 2 diabetes mellitus and the risk of open-angle glaucoma the Los Angeles Latino Eye Study.Ophthalmology, 115 2
-
M. Leske, A. Connell, Suh‐Yuh Wu, L. Hyman, A. Schachat (1995)
Risk factors for open-angle glaucoma. The Barbados Eye Study.Archives of ophthalmology, 113 7
-
H. Quigley (2009)
Can diabetes be good for glaucoma? Why can't we believe our own eyes (or data)?Archives of ophthalmology, 127 2
-
Brian Buckingham, D. Inman, W. Lambert, E. Oglesby, D. Calkins, Michael Steele, M. Vetter, N. Marsh-Armstrong, P. Horner (2008)
Progressive Ganglion Cell Degeneration Precedes Neuronal Loss in a Mouse Model of GlaucomaThe Journal of Neuroscience, 28
-
R. Casson, G. Chidlow, James Wood, N. Osborne (2004)
The effect of hyperglycemia on experimental retinal ischemia.Archives of ophthalmology, 122 3
-
S. Madsen-Bouterse, R. Kowluru (2008)
Oxidative stress and diabetic retinopathy: Pathophysiological mechanisms and treatment perspectivesReviews in Endocrine and Metabolic Disorders, 9
-
N. Kagansky, S. Levy, H. Knobler (2001)
The role of hyperglycemia in acute stroke.Archives of neurology, 58 8
-
N. Marina, N. Bull, K. Martin (2010)
A semiautomated targeted sampling method to assess optic nerve axonal loss in a rat model of glaucomaNature Protocols, 5
-
A. Rijk, H. Bloemendal (2000)
Alpha-B-Crystallin in NeuropathologyOphthalmologica, 214
-
A. Barber, E. Lieth, S. Khin, D. Antonetti, A. Buchanan, T. Gardner (1998)
Neural apoptosis in the retina during experimental and human diabetes. Early onset and effect of insulin.The Journal of clinical investigation, 102 4
-
K. Canola, B. Angénieux, M. Tekaya, A. Quiambao, M. Naash, F. Munier, D. Schorderet, Y. Arsenijévic (2007)
Retinal stem cells transplanted into models of late stages of retinitis pigmentosa preferentially adopt a glial or a retinal ganglion cell fate.Investigative ophthalmology & visual science, 48 1
-
R. Krueger, J. Ramos-Esteban (2007)
How might corneal elasticity help us understand diabetes and intraocular pressure?Journal of refractive surgery, 23 1
-
P. Mitchell, W. Smith, T. Chey, P. Healey (1997)
Open-angle glaucoma and diabetes: the Blue Mountains eye study, Australia.Ophthalmology, 104 4
-
M. Holman, G. Chidlow, J. Wood, R. Casson (2010)
The effect of hyperglycemia on hypoperfusion-induced injury.Investigative ophthalmology & visual science, 51 4
-
J. Wood, G. Chidlow, M. Graham, Neville Osborne (2005)
Energy substrate requirements for survival of rat retinal cells in culture: the importance of glucose and monocarboxylatesJournal of Neurochemistry, 93
-
M. Terada, H. Yasuda, R. Kikkawa (1998)
Delayed Wallerian degeneration and increased neurofilament phosphorylation in sciatic nerves of rats with streptozocin-induced diabetesJournal of the Neurological Sciences, 155
-
J. Melena, R. Safa, M. Graham, R. Casson, N. Osborne (2003)
The monocarboxylate transport inhibitor, α-cyano-4-hydroxycinnamate, has no effect on retinal ischemiaBrain Research, 989
-
B. Klein, R. Klein, S. Jensen (1994)
Open-angle glaucoma and older-onset diabetes. The Beaver Dam Eye Study.Ophthalmology, 101 7
-
D. Su, T. Wong, W. Wong, S. Saw, D. Tan, S. Shen, S. Loon, P. Foster, T. Aung (2008)
Diabetes, hyperglycemia, and central corneal thickness: the Singapore Malay Eye Study.Ophthalmology, 115 6
-
S. Baltan, D. Inman, Camelia Danilov, R. Morrison, D. Calkins, P. Horner (2010)
Metabolic Vulnerability Disposes Retinal Ganglion Cell Axons to Dysfunction in a Model of Glaucomatous DegenerationThe Journal of Neuroscience, 30
-
A. Broman, N. Congdon, K. Bandeen-Roche, H. Quigley (2007)
Influence of Corneal Structure, Corneal Responsiveness, and Other Ocular Parameters on Tonometric Measurement of Intraocular PressureJournal of Glaucoma, 16
-
H. Levkovitch-Verbin, H. Quigley, K. Martin, Danielle Valenta, Lisa Baumrind, M. Pease (2002)
Translimbal laser photocoagulation to the trabecular meshwork as a model of glaucoma in rats.Investigative ophthalmology & visual science, 43 2
- Publisher
- American Medical Association
- Copyright
- Copyright 2011 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
- ISSN
- 2168-6165
- eISSN
- 2168-6173
- DOI
- 10.1001/archophthalmol.2011.269
- pmid
- 21987677
- Publisher site
- See Article on Publisher Site
Abstract
LABORATORY SCIENCES Protection of Retinal Ganglion Cells and the Optic Nerve During Short-term Hyperglycemia in Experimental Glaucoma Andreas Ebneter, MD; Glyn Chidlow, DPhil; John P. M. Wood, DPhil; Robert J. Casson, MB, BS(Hons), DPhil Objective: To evaluate the neuroprotective effect of vival of retinal ganglion cell perikarya increased to a simi- short-term hyperglycemia on the retinal ganglion cell body lar extent in hyperglycemic rats. and axon in a rat model of experimental glaucoma. Conclusions: The optic nerve and retinal ganglion cells Methods: Using a well-described limbal laser tech- are partially protected by short-term hyperglycemia in nique, unilateral ocular hypertension was induced in 2 this rat model of experimental glaucoma. Energy sub- groups (26 per group) of Sprague-Dawley rats. One group strate availability may therefore play a role in glaucoma- remained normoglycemic; the other was rendered hy- tous optic neuropathy. perglycemic by means of an intraperitoneal injection of streptozocin. After 2 weeks of elevated intraocular pres- Clinical Relevance: Our findings, to some extent, sup- sure, axonal and retinal damage profiles were compared port the claims of the Ocular Hypertension Treatment using several histological techniques. Immunohisto- Study, in which diabetes appeared to protect against the chemical changes in the retina and
Journal
JAMA Ophthalmology – American Medical Association
Published: Oct 1, 2011