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PROPHYLAXIS OF THE COMMON COLD

PROPHYLAXIS OF THE COMMON COLD Abstract There can be drawn a fairly apt analogy between war and the invasion of the tissues of the upper respiratory tract by the organisms which give rise to the common cold. In accordance with this analogy, the invading forces in infections of the upper respiratory tract are the many pathogenic bacteria associated with respiratory disease. The defenses of the nose against such invasion are twofold—the front line, which consists of the mucous blanket and ciliated epithelium of the nasal mucosa, and the second line, represented in the natural immune responses of the tissues to such bacteria. The importance of maintaining an adequate first line of defense has been stressed by Proetz,1 Hilding,2 Lierle3 and others. They have pointed out the factors which tend to break down these defense mechanisms. The fifth column activities of a dry hot atmosphere, of metabolic disturbances, of dietary insufficiencies and the like are well known References 1. Proetz, A. W.: Effect of Temperature on Nasal Cilia , Arch. Otolaryng. 19:607 ( (May) ) 1934Crossref 2. Nasal Ciliated Epithelium, with Special Reference to Infection and Treatment , J. Laryng. & Otol. 49:557 ( (Oct.) ) 1934. 3. Hilding, A.: Physiology of Drainage of Nasal Mucus , Arch. Otolaryng. 15:92 ( (Jan.) ) 1932. 4. Lierle, D. M., and Moore, P. M.: Effects of Drugs on Ciliary Activity of Mucosa of Upper Respiratory Tract , Arch. Otolaryng. 19:55 ( (Jan.) ) 1934. 5. Diehl, H. S.; Baker, A. B., and Cowan, D. W.: Cold Vaccines: Evaluation Based on Controlled Study , J. A. M. A. 111:1168-1173 ( (Sept. 24) ) 1938. 6. Walsh, T. E.: Intranasal Vaccine Spray: Its Use in Prophylaxis Against Common Cold , Ann. Otol., Rhin. & Laryng. 49:875 ( (Dec.) ) 1940. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Otolaryngology American Medical Association

PROPHYLAXIS OF THE COMMON COLD

WALSH, THEODORE E.
Archives of Otolaryngology , Volume 34 (6) – Dec 1, 1941
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Publisher
American Medical Association
Copyright
Copyright © 1941 American Medical Association. All Rights Reserved.
ISSN
0003-9977
DOI
10.1001/archotol.1941.00660041187002
Publisher site
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Abstract

Abstract There can be drawn a fairly apt analogy between war and the invasion of the tissues of the upper respiratory tract by the organisms which give rise to the common cold. In accordance with this analogy, the invading forces in infections of the upper respiratory tract are the many pathogenic bacteria associated with respiratory disease. The defenses of the nose against such invasion are twofold—the front line, which consists of the mucous blanket and ciliated epithelium of the nasal mucosa, and the second line, represented in the natural immune responses of the tissues to such bacteria. The importance of maintaining an adequate first line of defense has been stressed by Proetz,1 Hilding,2 Lierle3 and others. They have pointed out the factors which tend to break down these defense mechanisms. The fifth column activities of a dry hot atmosphere, of metabolic disturbances, of dietary insufficiencies and the like are well known References 1. Proetz, A. W.: Effect of Temperature on Nasal Cilia , Arch. Otolaryng. 19:607 ( (May) ) 1934Crossref 2. Nasal Ciliated Epithelium, with Special Reference to Infection and Treatment , J. Laryng. & Otol. 49:557 ( (Oct.) ) 1934. 3. Hilding, A.: Physiology of Drainage of Nasal Mucus , Arch. Otolaryng. 15:92 ( (Jan.) ) 1932. 4. Lierle, D. M., and Moore, P. M.: Effects of Drugs on Ciliary Activity of Mucosa of Upper Respiratory Tract , Arch. Otolaryng. 19:55 ( (Jan.) ) 1934. 5. Diehl, H. S.; Baker, A. B., and Cowan, D. W.: Cold Vaccines: Evaluation Based on Controlled Study , J. A. M. A. 111:1168-1173 ( (Sept. 24) ) 1938. 6. Walsh, T. E.: Intranasal Vaccine Spray: Its Use in Prophylaxis Against Common Cold , Ann. Otol., Rhin. & Laryng. 49:875 ( (Dec.) ) 1940.

Journal

Archives of Otolaryngology – American Medical Association

Published: Dec 1, 1941

References

  • Effect of Temperature on Nasal Cilia
    Proetz , A. W.
  • Nasal Ciliated Epithelium, with Special Reference to Infection and Treatment
  • Physiology of Drainage of Nasal Mucus
    Hilding , A.
  • Effects of Drugs on Ciliary Activity of Mucosa of Upper Respiratory Tract
    Lierle , D. M., and Moore, P. M.
  • Cold Vaccines: Evaluation Based on Controlled Study
    Diehl , H. S.; Baker, A. B., and Cowan, D. W.
  • Intranasal Vaccine Spray: Its Use in Prophylaxis Against Common Cold
    Walsh , T. E.