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PROGRESSIVE SCLERODERMA OF THE SKIN WITH CYSTIC SCLERODERMAL CHANGES OF THE LUNGS

PROGRESSIVE SCLERODERMA OF THE SKIN WITH CYSTIC SCLERODERMAL CHANGES OF THE LUNGS Abstract PROGRESSIVE scleroderma has long been recognized as a disorder of a general character. Apart from the skin and its appendages, the underlying musculature, the fascia, the tendons, the mucous membrane of the mouth and the bones and joints are also characteristically involved. The sclerotic changes are not restricted only to organs bordering on the skin, but, as evidenced by the autopsy records so far published, may be encountered in internal organs too. Thus Ehrmann1 gave an enumeration of the internal organs concerned (esophagus, lungs, heart, kidneys, liver and incretory glands) and described their involvement in a way that leaves no doubt as to the specifically sclerodermal nature of the symptoms. Since that time, important evidence concerning the subject has been contributed by others too. Thus Podkaminskiy2 described peculiar changes in bone and Weissenbach3 functional disturbances of the esophagus associated with progressive scleroderma. Characteristic pulmonary changes had already References 1. Ehrmann, S.: Sclerodermie , in Jadassohn, J.: Handbuch der Haut- und Geschlechtskrankheiten , Berlin, Julius Springer, 1931, vol. 8, pt. (2) , pp. 804-819. 2. Podkaminskiy, N. A.: Acrosclerosis Hyperplastica Intraossea , Am. J. Roentgenol. 38:889-892 ( (Dec.) ) 1937. 3. Weissenbach, R. J., and others: Sclérodermie progressive: Syndrome de Thibierge-Weissenbach; ulcère de jambe et calcification en molletières; troubles oesphagiens , Bull. Soc. franç. de dermat. et syph. 44:2018-2024 ( (Dec.) ) 1937. 4. Finlay: Scleroderma, Middlesex Hosp. Rep. (1889), 1891, p. 29; 5. Luithlen, F., in Mraček, F.: Handbuch der Hautkrankeiten , Vienna, A. Hölder, 1904, vol. 3, p. 152. 6. von Notthafft, A.: Neuere Arbeiten und Ansichten über Sclerodermie , Centralbl. f. allg. Path. u. path. Anat. 9:870-960, 1898. 7. Matsui, S.: Ueber die Pathologie und Pathogenese von Sclerodermia universalis , Mitt. a. d. med. Fak. d. k. Univ. zu Tokyo 31:55-116, 1924; 8. Presse méd. 2:142, 1924. 9. Kraus, E. J.: Zur Pathogenese der diffusen Sklerodermie , Virchows Arch. f. path. Anat. 253:710-734, 1924.Crossref 10. Murphy, J. R.; Krainin, P., and Gerson, M. J.: Scleroderma with Pulmonary Fibrosis , J. A. M. A. 116:499-501 ( (Feb. 8) ) 1941.Crossref 11. Weiss, S.; Stead, E. A., Jr.; Warren, J. V., and Bailey, O. T.: Scleroderma Heart Disease, with Consideration of Certain Other Visceral Manifestations of Scleroderma , Arch. Int. Med. 71:749-776 ( (June) ) 1943.Crossref 12. Getzowa, S.: Pulmosclerosis Cystica and Pulmosclerosis Compacta in Scleroderma Progressiva , Arch. Path. 40:99-106 ( (Aug.) ) 1945. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology and Syphilology American Medical Association

PROGRESSIVE SCLERODERMA OF THE SKIN WITH CYSTIC SCLERODERMAL CHANGES OF THE LUNGS

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Publisher
American Medical Association
Copyright
Copyright © 1947 American Medical Association. All Rights Reserved.
ISSN
0096-6029
DOI
10.1001/archderm.1947.01520010005001
Publisher site
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Abstract

Abstract PROGRESSIVE scleroderma has long been recognized as a disorder of a general character. Apart from the skin and its appendages, the underlying musculature, the fascia, the tendons, the mucous membrane of the mouth and the bones and joints are also characteristically involved. The sclerotic changes are not restricted only to organs bordering on the skin, but, as evidenced by the autopsy records so far published, may be encountered in internal organs too. Thus Ehrmann1 gave an enumeration of the internal organs concerned (esophagus, lungs, heart, kidneys, liver and incretory glands) and described their involvement in a way that leaves no doubt as to the specifically sclerodermal nature of the symptoms. Since that time, important evidence concerning the subject has been contributed by others too. Thus Podkaminskiy2 described peculiar changes in bone and Weissenbach3 functional disturbances of the esophagus associated with progressive scleroderma. Characteristic pulmonary changes had already References 1. Ehrmann, S.: Sclerodermie , in Jadassohn, J.: Handbuch der Haut- und Geschlechtskrankheiten , Berlin, Julius Springer, 1931, vol. 8, pt. (2) , pp. 804-819. 2. Podkaminskiy, N. A.: Acrosclerosis Hyperplastica Intraossea , Am. J. Roentgenol. 38:889-892 ( (Dec.) ) 1937. 3. Weissenbach, R. J., and others: Sclérodermie progressive: Syndrome de Thibierge-Weissenbach; ulcère de jambe et calcification en molletières; troubles oesphagiens , Bull. Soc. franç. de dermat. et syph. 44:2018-2024 ( (Dec.) ) 1937. 4. Finlay: Scleroderma, Middlesex Hosp. Rep. (1889), 1891, p. 29; 5. Luithlen, F., in Mraček, F.: Handbuch der Hautkrankeiten , Vienna, A. Hölder, 1904, vol. 3, p. 152. 6. von Notthafft, A.: Neuere Arbeiten und Ansichten über Sclerodermie , Centralbl. f. allg. Path. u. path. Anat. 9:870-960, 1898. 7. Matsui, S.: Ueber die Pathologie und Pathogenese von Sclerodermia universalis , Mitt. a. d. med. Fak. d. k. Univ. zu Tokyo 31:55-116, 1924; 8. Presse méd. 2:142, 1924. 9. Kraus, E. J.: Zur Pathogenese der diffusen Sklerodermie , Virchows Arch. f. path. Anat. 253:710-734, 1924.Crossref 10. Murphy, J. R.; Krainin, P., and Gerson, M. J.: Scleroderma with Pulmonary Fibrosis , J. A. M. A. 116:499-501 ( (Feb. 8) ) 1941.Crossref 11. Weiss, S.; Stead, E. A., Jr.; Warren, J. V., and Bailey, O. T.: Scleroderma Heart Disease, with Consideration of Certain Other Visceral Manifestations of Scleroderma , Arch. Int. Med. 71:749-776 ( (June) ) 1943.Crossref 12. Getzowa, S.: Pulmosclerosis Cystica and Pulmosclerosis Compacta in Scleroderma Progressiva , Arch. Path. 40:99-106 ( (Aug.) ) 1945.

Journal

Archives of Dermatology and SyphilologyAmerican Medical Association

Published: Jan 1, 1947

References