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Prognostic Implications of the Urinary Albumin to Creatinine Ratio in Veterans of Different Ages With Diabetes

Prognostic Implications of the Urinary Albumin to Creatinine Ratio in Veterans of Different Ages... ORIGINAL INVESTIGATION Prognostic Implications of the Urinary Albumin to Creatinine Ratio in Veterans of Different Ages With Diabetes Ann M. O’Hare, MD, MA; Susan M. Hailpern, DrPH, MS; Meda E. Pavkov, MD, PhD; Nilka Rios-Burrows, MPH; Indra Gupta, PhD; Charles Maynard, PhD; Jeff Todd-Stenberg, BA; Rudolph A. Rodriguez, MD; Brenda R. Hemmelgarn, MD, PhD; Rajiv Saran, MD; Desmond E. Williams, MD, PhD Background: Albuminuria is associated with an in- tients with an eGFR less than 60 mL/min/1.73 m , 72% creased risk of death independent of level of renal func- of those younger than 65 years, 74% of those 65 to 74 tion. Whether this association is similar for adults of all years old, and 59% of those 75 years and older had an ages is not known. eGFR of 45 to 59 mL/min/1.73 m . In all age groups, less than 35% of these patients had albuminuria (ie, ACR30 Methods: We examined the association between the al- mg/g). In patients 75 years and older, the ACR was in- bumin to creatinine ratio (ACR) and all-cause mortality dependently associated with an increased risk of death after stratification by estimated glomerular filtration rate at all levels of eGFR after adjusting http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Internal Medicine American Medical Association

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Publisher
American Medical Association
Copyright
Copyright 2010 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6106
eISSN
2168-6114
DOI
10.1001/archinternmed.2010.129
pmid
20548004
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL INVESTIGATION Prognostic Implications of the Urinary Albumin to Creatinine Ratio in Veterans of Different Ages With Diabetes Ann M. O’Hare, MD, MA; Susan M. Hailpern, DrPH, MS; Meda E. Pavkov, MD, PhD; Nilka Rios-Burrows, MPH; Indra Gupta, PhD; Charles Maynard, PhD; Jeff Todd-Stenberg, BA; Rudolph A. Rodriguez, MD; Brenda R. Hemmelgarn, MD, PhD; Rajiv Saran, MD; Desmond E. Williams, MD, PhD Background: Albuminuria is associated with an in- tients with an eGFR less than 60 mL/min/1.73 m , 72% creased risk of death independent of level of renal func- of those younger than 65 years, 74% of those 65 to 74 tion. Whether this association is similar for adults of all years old, and 59% of those 75 years and older had an ages is not known. eGFR of 45 to 59 mL/min/1.73 m . In all age groups, less than 35% of these patients had albuminuria (ie, ACR30 Methods: We examined the association between the al- mg/g). In patients 75 years and older, the ACR was in- bumin to creatinine ratio (ACR) and all-cause mortality dependently associated with an increased risk of death after stratification by estimated glomerular filtration rate at all levels of eGFR after adjusting

Journal

JAMA Internal MedicineAmerican Medical Association

Published: Jun 14, 2010

References

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