Abstract Primary tumor of the optic nerve is not common, although in the literature of the past sixty-four years about 300 cases of tumor of the optic nerve have been reported. Four have been observed at the Massachusetts' Eye and Ear Infirmary in Boston in thirty-six years, and one, at the Wills Hospital in Philadelphia in twelve years. Hudson1 found that this type of tumor was more common in females than in males and that 75 per cent of the patients were in the first decade of life, which led some authors to suggest that the neoplasm is congenital. The tumor may spread from the intra-orbital to the intracranial portion of the optic nerve through the optic foramen or from the intracranial to the intra-orbital portion of the nerve. In possibly the majority of the cases reported the neoplasm has occurred in the intra-orbital portion of the References 1. Hudson, A. C.: Primary Tumors of the Optic Nerve , Roy. London Ophth. Hosp. Rep. 18:317 ( (July) ) 1912. 2. Whitnall, S. E.: Anatomy of the Human Orbit and Accessory Organs of Vision , New York, Oxford University Press, 1932. 3. Martin, P., and Cushing, H.: Primary Giomas of the Chiasm and Optic Nerves in Their Intracranial Portion , Arch. Ophth. 52:209 ( (May) ) 1923. 4. Verhoeff, F. H.: Primary Intraneural Tumors (Gliomas) of the Optic Nerves in Their Intracranial Portion , Arch. Opth. 52:209 ( (May) ) 1923. 5. Grinker, R. R.: Tumors of the Optic Nerve , Arch. Ophth. 4:497 ( (Oct.) ) 1930.Crossref 6. DeLong, P.: Primary Tumors of Optic Nerve: Report of a Case , Am. J. Ophth. 17:797 ( (Sept.) ) 1934. 7. Permission was granted by Dr. Max Minor Peet, of the department of neurosurgery, for the use of the operative report in each case and by Dr. Konstantin Lowenberg, of the department of neuropathology, for the use of the pathologic description in each case.
Archives of Ophthalmology – American Medical Association
Published: Jul 1, 1936
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