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Epic Investigators (1994)
Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty.The New England journal of medicine, 330 14
C. Grines, K. Browne, J. Marco, D. Rothbaum, G. Stone, James O'Keefe, P. Overlie, B. Donohue, N. Chelliah, G. Timmis, R. Vlietstra, M. Strzelecki, S. Puchrowicz-Ochocki, W. O’Neill (1993)
A Comparison of Immediate Angioplasty with Thrombolytic Therapy for Acute Myocardial InfarctionThe New England Journal of Medicine, 328
R. Gibbons, D. Holmes, G. Reeder, K. Bailey, M. Hopfenspirger, B. Gersh (1993)
Immediate angioplasty compared with the administration of a thrombolytic agent followed by conservative treatment for myocardial infarction. The Mayo Coronary Care Unit and Catheterization Laboratory Groups.The New England journal of medicine, 328 10
M. Simoons, S. Ellis (1997)
A clinical trial comparing primary coronary angioplasty with tissue plasminogen activator for acute myocardial infarction.The New England journal of medicine, 336 23
W. O'neill, G. Timmis, P. Bourdillon, P. Lai, V. Ganghadarhan, J. Walton, R. Ramos, N. Laufer, Seymor Gordon, M. Schork, B. Pitt (1986)
A prospective randomized clinical trial of intracoronary streptokinase versus coronary angioplasty for acute myocardial infarction.The New England journal of medicine, 314 13
A. Volpi, A. Maggioni, M. Franzosi, S. Pampallona, F. Mauri, G. Tognoni (1987)
In-hospital prognosis of patients with acute myocardial infarction complicated by primary ventricular fibrillation.The New England journal of medicine, 317 5
W. Weaver, R. Simes, A. Betriu, C. Grines, F. Zijlstra, Eulogio García, L. Grinfeld, R. Gibbons, E. Ribeiro, M. Dewood, F. Ribichini (1997)
Comparison of primary coronary angioplasty and intravenous thrombolytic therapy for acute myocardial infarction : A quantitative reviewJAMA, 278
N. Every, L. Parsons, M. Hlatky, Jenny Martin, Weaver Wd (1996)
A comparison of thrombolytic therapy with primary coronary angioplasty for acute myocardial infarction. Myocardial Infarction Triage and Intervention Investigators.The New England journal of medicine, 335 17
L. Maillard, M. Ziol, C. Feuvre, O. Tahlil, L. Feldman, D. Branellec, M. Perricaudet, P. Steg (1996)
Improved efficiency of percutaneous adenoviral-mediated arterial gene transfer by pre-treatment with elastaseJournal of the American College of Cardiology, 27
K. Michels, S. Yusuf (1995)
Does PTCA in acute myocardial infarction affect mortality and reinfarction rates? A quantitative overview (meta-analysis) of the randomized clinical trials.Circulation, 91 2
J. Herlitz (1994)
Indications for fibrinolytic therapy in suspected acute myocardial infarction : collaborative overview of early mortality and major morbidity results from all randomised trials of more than 1000 patientsThe Lancet, 343
C. Miguel, P. Serruys, P. Ruygrok, H. Suryapranata, S. Klugmann, P. Urban, P. Heijer, K. Koch, R. Simon, M. Morice, P. Crean, H. Bonnier, W. Wijns, N. Danchin, C. Bourdonnec, M. Morel, G. Mast (1996)
Continued benefit of coronary stenting versus balloon angioplasty: one-year clinical follow-up of Benestent trial. Benestent Study Group.Journal of the American College of Cardiology, 27 2
In this issue of The Journal, Weaver and colleagues1 provide a careful quantitative review of the available data from randomized trials comparing primary percutaneous transluminal coronary angioplasty (PTCA) with thrombolytic therapy in patients with acute myocardial infarction. This analysis of 10 trials includes 2606 patients and reports a reduction in mortality (odds ratio, 0.66; 95% confidence interval [CI], 0.46-0.94), in the composite of mortality and reinfarction (odds ratio, 0.58; 95% CI, 0.44-0.76), and in stroke (odds ratio, 0.35; 95% CI, 0.14-0.77) with the use of PTCA. However, before the data from these analyses are considered persuasive enough to conclusively establish the superiority of primary PTCA over thrombolytic therapy, 3 key questions must be addressed. See also p 2093. First, are there potential biases that could have inflated the results of the individual trials or this meta-analysis? Several potential biases both within each trial and in the authors' metaanalysis should
JAMA – American Medical Association
Published: Dec 17, 1997
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