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Preoperatively Administered Antibiotics: Their Effect on Bacterial Counts of the Eyelids

Preoperatively Administered Antibiotics: Their Effect on Bacterial Counts of the Eyelids Abstract Seven different prophylactic regimens were evaluated for their effectiveness in decreasing or eradicating bacteria on the eyelids before surgery. The antibiotics used were a solution of polymyxin, neomycin, and gramicidin (in three schedules); an ointment of polymyxin, neomycin, and bacitracin (one schedule); chloramphenicol, 0.5% solution (one schedule); and gentamycin, 1.0% solution (two schedules). Six of the seven schedules (all but chloramphenicol in its single schedule) reduced bacterial counts on the lids when compared with control eyes receiving no antibiotics. None of the schedules was very effective, however. The most effective (gentamycin drops given every ten minutes for two hours) only eradicated bacteria in 44% of the eyes treated. We concluded that an effective antibiotic by a practical schedule would reduce the lid bacterial count but could not be relied on to sterilize the lids routinely. References 1. Burns RP: Postoperative infections in an ophthalmologic hospital: With comments upon bacteriophage typing of staphylococci as a preventative tool . Amer J Ophthal 48:519-526, 1959. 2. Allen HF, Mangiaracine AB: Bacterial endophthalmitis after cataract extraction . Arch Ophthal 72:454-462, 1964.Crossref 3. Allansmith MR, Anderson RP, Butterworth M: The meaning of preoperative cultures in ophthalmology . Trans Amer Acad Ophthal Otolaryng 73:683-690, 1969. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Preoperatively Administered Antibiotics: Their Effect on Bacterial Counts of the Eyelids

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Publisher
American Medical Association
Copyright
Copyright © 1972 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1972.01000020157007
Publisher site
See Article on Publisher Site

Abstract

Abstract Seven different prophylactic regimens were evaluated for their effectiveness in decreasing or eradicating bacteria on the eyelids before surgery. The antibiotics used were a solution of polymyxin, neomycin, and gramicidin (in three schedules); an ointment of polymyxin, neomycin, and bacitracin (one schedule); chloramphenicol, 0.5% solution (one schedule); and gentamycin, 1.0% solution (two schedules). Six of the seven schedules (all but chloramphenicol in its single schedule) reduced bacterial counts on the lids when compared with control eyes receiving no antibiotics. None of the schedules was very effective, however. The most effective (gentamycin drops given every ten minutes for two hours) only eradicated bacteria in 44% of the eyes treated. We concluded that an effective antibiotic by a practical schedule would reduce the lid bacterial count but could not be relied on to sterilize the lids routinely. References 1. Burns RP: Postoperative infections in an ophthalmologic hospital: With comments upon bacteriophage typing of staphylococci as a preventative tool . Amer J Ophthal 48:519-526, 1959. 2. Allen HF, Mangiaracine AB: Bacterial endophthalmitis after cataract extraction . Arch Ophthal 72:454-462, 1964.Crossref 3. Allansmith MR, Anderson RP, Butterworth M: The meaning of preoperative cultures in ophthalmology . Trans Amer Acad Ophthal Otolaryng 73:683-690, 1969.

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Feb 1, 1972

References