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Pregabalin for the Treatment of Men With Chronic Prostatitis/Chronic Pelvic Pain Syndrome

Pregabalin for the Treatment of Men With Chronic Prostatitis/Chronic Pelvic Pain Syndrome ORIGINAL INVESTIGATION Pregabalin for the Treatment of Men With Chronic Prostatitis/Chronic Pelvic Pain Syndrome A Randomized Controlled Trial Michel A. Pontari, MD; John N. Krieger, MD; Mark S. Litwin, MD; Paige C. White, MD; Rodney U. Anderson, MD; Mary McNaughton-Collins, MD; J. Curtis Nickel, MD; Daniel A. Shoskes, MD; Richard B. Alexander, MD; Michael O’Leary, MD; Scott Zeitlin, MD; Shannon Chuai, MS; J. Richard Landis, PhD; Liyi Cen, MS; Kathleen J. Propert, ScD; John W. Kusek, PhD; Leroy M. Nyberg Jr, MD, PhD; Anthony J. Schaeffer, MD; for the Chronic Prostatitis Collaborative Research Network-2 Background: Evidence suggests that the urogenital pain (47.2%) reported at least a 6-point decrease in the NIH- of chronic prostatitis/chronic pelvic pain syndrome (CP/ CPSI total score at 6 weeks compared with 35.8% (38 of CPPS) may be neuropathic. 106 men) assigned to receive placebo (P=.07, exact Mantel- Haenszel test, adjusting for clinical sites). Compared with Methods: This randomized, double-blind, placebo- the placebo group, men assigned to receive pregabalin ex- controlled trial was conducted across 10 tertiary care cen- perienced reductions in the NIH-CPSI total score and sub- ters in North America to determine whether pregabalin, scores (P.05), a higher Global Response Assessment re- which http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Internal Medicine American Medical Association

Pregabalin for the Treatment of Men With Chronic Prostatitis/Chronic Pelvic Pain Syndrome

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References (34)

Publisher
American Medical Association
Copyright
Copyright 2010 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6106
eISSN
2168-6114
DOI
10.1001/archinternmed.2010.319
pmid
20876412
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL INVESTIGATION Pregabalin for the Treatment of Men With Chronic Prostatitis/Chronic Pelvic Pain Syndrome A Randomized Controlled Trial Michel A. Pontari, MD; John N. Krieger, MD; Mark S. Litwin, MD; Paige C. White, MD; Rodney U. Anderson, MD; Mary McNaughton-Collins, MD; J. Curtis Nickel, MD; Daniel A. Shoskes, MD; Richard B. Alexander, MD; Michael O’Leary, MD; Scott Zeitlin, MD; Shannon Chuai, MS; J. Richard Landis, PhD; Liyi Cen, MS; Kathleen J. Propert, ScD; John W. Kusek, PhD; Leroy M. Nyberg Jr, MD, PhD; Anthony J. Schaeffer, MD; for the Chronic Prostatitis Collaborative Research Network-2 Background: Evidence suggests that the urogenital pain (47.2%) reported at least a 6-point decrease in the NIH- of chronic prostatitis/chronic pelvic pain syndrome (CP/ CPSI total score at 6 weeks compared with 35.8% (38 of CPPS) may be neuropathic. 106 men) assigned to receive placebo (P=.07, exact Mantel- Haenszel test, adjusting for clinical sites). Compared with Methods: This randomized, double-blind, placebo- the placebo group, men assigned to receive pregabalin ex- controlled trial was conducted across 10 tertiary care cen- perienced reductions in the NIH-CPSI total score and sub- ters in North America to determine whether pregabalin, scores (P.05), a higher Global Response Assessment re- which

Journal

JAMA Internal Medicine – American Medical Association

Published: Sep 27, 2010

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