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Predictors of Corneal Perforation or Need for Therapeutic Keratoplasty in Severe Fungal Keratitis

Predictors of Corneal Perforation or Need for Therapeutic Keratoplasty in Severe Fungal Keratitis Key PointsQuestionDo baseline clinical features predict the risk of developing corneal perforation and/or undergoing therapeutic penetrating keratoplasty in infectious keratitis? FindingsIn this post hoc analysis of patients in the Mycotic Ulcer Treatment Trial II, we found that a baseline presence of hypopyon and infiltrate depth and size were statistically significant predictors of corneal perforation and/or the need for therapeutic penetrating keratoplasty. MeaningIdentifying patients who are at high risk of experiencing a poor outcome may be useful to allocate resources, particularly in resource-poor settings. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Ophthalmology American Medical Association

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References (15)

Publisher
American Medical Association
Copyright
Copyright 2017 American Medical Association. All Rights Reserved.
ISSN
2168-6165
eISSN
2168-6173
DOI
10.1001/jamaophthalmol.2017.2914
pmid
28817744
Publisher site
See Article on Publisher Site

Abstract

Key PointsQuestionDo baseline clinical features predict the risk of developing corneal perforation and/or undergoing therapeutic penetrating keratoplasty in infectious keratitis? FindingsIn this post hoc analysis of patients in the Mycotic Ulcer Treatment Trial II, we found that a baseline presence of hypopyon and infiltrate depth and size were statistically significant predictors of corneal perforation and/or the need for therapeutic penetrating keratoplasty. MeaningIdentifying patients who are at high risk of experiencing a poor outcome may be useful to allocate resources, particularly in resource-poor settings.

Journal

JAMA OphthalmologyAmerican Medical Association

Published: Sep 17, 2017

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