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ORIGINAL INVESTIGATION Predictive Relationship Between Depression and Physical Functioning After Coronary Surgery Friederike Kendel, PhD; Götz Gelbrich, PhD; Markus Wirtz, PhD; Elke Lehmkuhl, MD; Nina Knoll, PhD; Roland Hetzer, MD; Vera Regitz-Zagrosek, MD Background: Depression is a prevalent condition in pa- crease in physical functioning ( = −0.15 [P .001]; T1-T2 tients undergoing coronary artery bypass graft surgery = −0.17 [P .001]), but not the other way around. T2-T3 (CABG) and is often associated with a less favorable health Multigroup comparisons revealed one moderator effect: status. The aim of this study was to investigate the rela- in patients with systolic heart failure (left ventricular ejec- tionship between depression and physical functioning in tion fraction [LVEF], 45%), the effect of depression on patients undergoing CABG. physical functioning from T2 to T3 was significantly stron- ger than in patients with preserved LVEF ( = −0.30 T2-T3 Methods: The analyses were based on a sample of 883 2 [P .001] vs = −0.14 [P .001]; = 3.885 T2-T3 diff consecutive subjects (aged 35-93 years; 19.8% women) [P = .049]). undergoing CABG. Depression was assessed using the Pa- tient Health Questionnaire (PHQ); the subscale “physi- Conclusions: More attention should be
JAMA Internal Medicine – American Medical Association
Published: Oct 25, 2010
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