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Prediction of Functional Loss in Glaucoma From Progressive Optic Disc Damage

Prediction of Functional Loss in Glaucoma From Progressive Optic Disc Damage CLINICAL SCIENCES Prediction of Functional Loss in Glaucoma From Progressive Optic Disc Damage Felipe A. Medeiros, MD, PhD; Luciana M. Alencar, MD; Linda M. Zangwill, PhD; Christopher Bowd, PhD; Pamela A. Sample, PhD; Robert N. Weinreb, MD Objective: To evaluate the ability of progressive optic iate. Predictive accuracy was evaluated using a modified disc damage detected by assessment of longitudinal ste- R index. reophotographs to predict future development of func- tional loss in those with suspected glaucoma. Results: Progressive optic disc damage had a hazard ra- tio of 25.8 (95% confidence interval, 16.0-41.7) and was Methods: The study included 639 eyes of 407 patients the most important risk factor for development of vi- 2 2 with suspected glaucoma followed up for an average of sual field loss with an R of 79%. The R s for other pre- 8.0 years with annual standard automated perimetry vi- dictive factors ranged from 6% to 26%. sual field and optic disc stereophotographs. All patients had normal and reliable standard automated perimetry Conclusions: Presence of progressive optic disc dam- results at baseline. Conversion to glaucoma was defined age on stereophotographs was a highly predictive factor as development of 3 consecutive abnormal visual fields http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Ophthalmology American Medical Association

Prediction of Functional Loss in Glaucoma From Progressive Optic Disc Damage

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Publisher
American Medical Association
Copyright
Copyright 2009 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6165
eISSN
2168-6173
DOI
10.1001/archophthalmol.2009.276
pmid
19822839
Publisher site
See Article on Publisher Site

Abstract

CLINICAL SCIENCES Prediction of Functional Loss in Glaucoma From Progressive Optic Disc Damage Felipe A. Medeiros, MD, PhD; Luciana M. Alencar, MD; Linda M. Zangwill, PhD; Christopher Bowd, PhD; Pamela A. Sample, PhD; Robert N. Weinreb, MD Objective: To evaluate the ability of progressive optic iate. Predictive accuracy was evaluated using a modified disc damage detected by assessment of longitudinal ste- R index. reophotographs to predict future development of func- tional loss in those with suspected glaucoma. Results: Progressive optic disc damage had a hazard ra- tio of 25.8 (95% confidence interval, 16.0-41.7) and was Methods: The study included 639 eyes of 407 patients the most important risk factor for development of vi- 2 2 with suspected glaucoma followed up for an average of sual field loss with an R of 79%. The R s for other pre- 8.0 years with annual standard automated perimetry vi- dictive factors ranged from 6% to 26%. sual field and optic disc stereophotographs. All patients had normal and reliable standard automated perimetry Conclusions: Presence of progressive optic disc dam- results at baseline. Conversion to glaucoma was defined age on stereophotographs was a highly predictive factor as development of 3 consecutive abnormal visual fields

Journal

JAMA OphthalmologyAmerican Medical Association

Published: Oct 1, 2009

References