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Predicting Risk of Kidney Disease

Predicting Risk of Kidney Disease Opinion EDITORIAL Is Risk-Based Kidney Care on the Horizon? Sri Lekha Tummalapalli, MD, MBA; Michelle M. Estrella, MD, MHS Chronic kidney disease (CKD) causes an enormous human and end points, 5 of 13 study populations (38%) showed a slope be- financial toll worldwide. In the United States alone, an esti- tween 0.80 and 1.25 for eGFR of less than 45 mL/min/1.73 m , mated 37 million persons have CKD, and its incidence glob- and 4 of 11 study populations (36%) showed a slope between 1,2 2 ally is rising. Patients with 0.80 and 1.25 for eGFR of less than 30 mL/min/1.73 m . CKD are at incrementally in- An important consideration in interpreting this work is that Related article page 2104 creased risk for major cardio- these risk prediction equations assume that key health fac- vascular events as their dis- tors have been measured, particularly eGFR. In clinical set- ease progresses, and several million will progress to kidney tings, these laboratory measurements may have been per- failure. Early, effective management of risk factors, such formed based on the physician’s perception of the patient’s CKD as hypertension and diabetes, is imperative to prevent the risk and thus may affect the http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Predicting Risk of Kidney Disease

JAMA , Volume 322 (21) – Dec 3, 2019

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Publisher
American Medical Association
Copyright
Copyright 2019 American Medical Association. All Rights Reserved.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2019.17378
Publisher site
See Article on Publisher Site

Abstract

Opinion EDITORIAL Is Risk-Based Kidney Care on the Horizon? Sri Lekha Tummalapalli, MD, MBA; Michelle M. Estrella, MD, MHS Chronic kidney disease (CKD) causes an enormous human and end points, 5 of 13 study populations (38%) showed a slope be- financial toll worldwide. In the United States alone, an esti- tween 0.80 and 1.25 for eGFR of less than 45 mL/min/1.73 m , mated 37 million persons have CKD, and its incidence glob- and 4 of 11 study populations (36%) showed a slope between 1,2 2 ally is rising. Patients with 0.80 and 1.25 for eGFR of less than 30 mL/min/1.73 m . CKD are at incrementally in- An important consideration in interpreting this work is that Related article page 2104 creased risk for major cardio- these risk prediction equations assume that key health fac- vascular events as their dis- tors have been measured, particularly eGFR. In clinical set- ease progresses, and several million will progress to kidney tings, these laboratory measurements may have been per- failure. Early, effective management of risk factors, such formed based on the physician’s perception of the patient’s CKD as hypertension and diabetes, is imperative to prevent the risk and thus may affect the

Journal

JAMAAmerican Medical Association

Published: Dec 3, 2019

References