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/lp/american-medical-association/postnatal-prophylaxis-of-chlamydial-conjunctivitis-oHgTRCOdRn
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- Publisher
- American Medical Association
- Copyright
- Copyright © 1981 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
- ISSN
- 0098-7484
- eISSN
- 1538-3598
- DOI
- 10.1001/jama.1981.03320200011006
- Publisher site
- See Article on Publisher Site
Abstract
To the Editor.— We would like to offer several comments on the recent article by Hammerschlag et al (1980; 244:2291) on postnatal prophylaxis of chlamydial conjunctivitis by use of topical erythromycin ointment. This article hypothesizes that topical tetracycline may not be as effective as erythromycin in preventing ophthalmia neonatorum from Chlamydia trachomatis and mentions the occurrence of five cases within two months in infants who had received tetracycline ointment for ocular prophylaxis after birth at Parkland Memorial Hospital, Dallas. We have more recent data from the same hospital that suggest the ineffectiveness of tetracycline. Between December 1977 and December 1980, all infants born at Parkland Memorial Hospital received either single-dose intramuscular aqueous penicillin G (13,949 neonates) or 1% topical tetracycline ointment (13,598 infants) within 60 minutes of birth in a study of the prophylaxis of neonatal group B streptococcal infections.1 During the same period, we conducted a study of
Journal
JAMA – American Medical Association
Published: Nov 20, 1981