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POSTANGINAL SEPSIS

POSTANGINAL SEPSIS Abstract Septicemia may be due to a number of causes. It is important to determine the exact cause in order that proper treatment may be instituted. The purpose of this paper is to call attention to one cause of septicemia often overlooked by the physician, namely, septic phlebitis of the internal jugular vein or of one of its branches.1 This condition is usually called postanginal sepsis or postanginal pyemia2 because it almost always follows an infection of the throat. Failure to recognize this dangerous disease has resulted in many fatalities. Early diagnosis and operation may save the life of the patient. Few reports of cases of postanginal sepsis are found in the American literature, although German and French observers have published many. Two cases are reported here to illustrate the clinical picture and the diagnosis of this entity. REPORT OF CASES Case 1. —D. W., a white girl of References 1. Mosher, H. P.: Submaxillary Fossa Approach to Deep Pus in the Neck , Tr. Am. Acad. Ophth. 34:19, 1929. 2. Abt, I. A.: Postanginal Sepsis , J. Pediat. 1:8 ( (July) ) 1932.Crossref 3. Waldapfel, R.: Die postanginöse Pyämie , Ztschr. f. Hals-, Nasen- u. Ohrenh. 23:178, 1929. 4. Burchardt, S.: Ein Beitrag zur Pathogenese der postanginösen Sepsis , Ztschr. f. Hals-, Nasen- u. Ohrenh. 23:97, 1929. 5. Beck, A. L.: Deep Neck Infection , Ann. Otol., Rhin. & Laryng. 48:940 ( (Dec.) ) 1939. 6. Hirsch, C.: Septicemia Following Tonsillitis , New York State J. Med. 35:767 ( (Aug. 1) ) 1935. 7. Reye, E.: Zur Pyämie nach Angina , Med. Welt 4:1791 ( (Dec. 13) ) 1930. 8. Mosher, H. P.: Deep Cervical Abscess and Thrombosis of the Internal Jugular Vein , Laryngoscope 30:365 ( (June) ) 1920. 9. Hall, C.: The Parapharyngeal Space , Ann. Otol., Rhin. & Laryng. 43:793 ( (Sept.) ) 1934. 10. Shapiro, S. L.: Deep Cervical Infection Following Tonsillectomy , Arch. Otolaryng. 11:201 ( (June) ) 1930. 11. Deering, W., and Brennemann, J.: Acute Abscess of the Throat , J. A. M. A. 118: 1171 ( (April 4) ) 1942. 12. Beck, A. L.: A Study of Twenty-Four Cases of Neck Infection , Tr. Am. Acad. Ophth. 37:342, 1932. 13. Haymann, L.: Erhebungen über die tonsillogene Sepsis , Ztschr. f. Hals-, Nasen- u. Ohrenh. 35:288, 1934. 14. Kissling, K.: Ueber postanginöse Sepsis , München. med. Wchnschr. 76:1163 ( (July 12) ) 1929. 15. Hall, C.: Sepsis Following Pharyngeal Infections , Ann. Otol., Rhin. & Laryng. 48:905 ( (Dec.) ) 1939. 16. Hirsch.3b 17. Reuben, M. S.: Postanginal Sepsis , Arch. Pediat. 52:152 ( (March) ) 1935. 18. Shapiro.5b 19. Beck, A. L.: Parapharyngeal Infections and Internal Jugular Vein Thrombosis: Diagnosis and Treatment , Laryngoscope 44:431 ( (June) ) 1934. 20. Reuben.8a 21. Waldapfel, R.: Post-Tonsillitis Pyemia , Tr. Am. Acad. Ophth. 33:291, 1928. 22. Hirsch.3b 23. Dixon, O. J., and Helwig, F. C.: Thrombophlebitis of the Internal Jugular Vein as a Complication of Tonsillitis , Ann. Otol., Rhin. & Laryng. 39:1137 ( (Dec.) ) 1930. 24. Joel, W.: Ueber die postanginöse Pyämie und ihre Verbreitungswege , Deutsche med. Wchnschr. 55:2133 ( (Dec. 20) ) 1929. 25. Hirsch.3b 26. Mosher.4 27. Hall.7b 28. Fraenkel, E.: Pyämie nach Angina , Deutsche med. Wchnschr. 52:93 ( (Jan. 15) ) 1926.Crossref 29. Waldapfel.10a 30. Hall.7b 31. Beck.9a 32. Waldapfel.10a 33. Knick: Die operative Heilung der tonsillären Sepsis , Ztschr. f. Hals-, Nasen- u. Ohrenh. 18:546, 1927-1928. 34. Waldapfel.10a 35. Dixon and Helwig.11a 36. Burchardt.2c 37. Beck.6b 38. Knick.14 39. Hirsch.3b 40. Mosher.4 41. Dixon and Helwig.11a 42. Bertelsmann, R.: Ueber Postanginöse Sepsis sive Bakterämie , Zentralbl. f. Chir. 54:642 ( (March 12) ) 1927. 43. Rubin, H.: Pyemia Following Acute Tonsillar Infections , Arch. Otolaryng 17:183 ( (Feb.) ) 1933.Crossref 44. Kissling.7a 45. Bertelsmann, R.: Postanginöse Sepsis und die Lymphbahnen , Zentralbl. f. Chir. 54: 1949 ( (July 30) ) 1927. 46. Beck.6b 47. Hall.7b 48. Kissling.7a 49. Dixon and Helwig.11a 50. Hirsch.3b 51. Beck.6b 52. Hall.7b 53. Hirsch.4b 54. Beck.9a 55. Matis, E. I.: Two Unusual Cases of Postanginal Sepsis , Ann. Otol., Rhin. & Laryng. 49:559 ( (June) ) 1940. 56. Salinger, S., and Pearlman, S. J.: Hemorrhage from Pharyngeal and Peritonsillar Abscess , Arch. Otolaryng. 18:464 ( (Oct.) ) 1933. 57. Kissling.7a 58. Dixon and Helwig.11a 59. Knick.14 60. Long, J. W.: Excision of Internal Jugular Vein for Streptococcic Thrombi Vein and Cavernous Sinus Causing Paralysis of Orbital Muscles , Surg., Gynec. & Obst. 14:86, 1912. 61. Claus, H.: Acht und zwanzig Fälle von Pyämie nach Angina , Ztschr. f. Hals-, Nasen- u. Ohrenh. 21:114, 1929. 62. Hirsch.3b 63. Rubin.18b 64. Stahl, R.: Zur Kenntis der Thrombophlebitis und Sepsis postanginosa , Deutsche med. Wchnschr. 53:186 ( (Jan. 28) ) 1927. 65. Fraenkel.12 66. Mlechlin, B., cited by Matis.23 67. Claus, H.: Bemerkungen zur Pyämie nach Angina , Ztschr. f. Hals-, Nasen- u. Ohrenh. 18:557, 1927. 68. Hall.7b 69. Claus.26b 70. Hall.7b 71. Claus.26b 72. Claus.29 73. Hall.7b 74. Beck.9a 75. Rubin.18b 76. Matis.23 77. Goodman, C.: Primary Jugular Thrombosis Due to Tonsil Infection , Ann. Otol., Rhin. & Laryng. 26:527, 1917. 78. Abt.2a 79. Beck.3a 80. Beck.6b 81. Stahl.27a 82. Hall.7b 83. Claus.29 84. Hirsch.3b 85. Hall.7b 86. Beck.9a 87. Claus.26b 88. White, P. D.: Heart Disease , ed. 2, New York, The Macmillan Company, 1931, p. 344. 89. Artuse, C., cited by Abt.2a 90. Kracke, R. R., and Garver, H. E.: Diseases of the Blood and Atlas of Hematology, with Clinical and Hematologic Descriptions of the Blood Diseases Including a Section on Technics and Terminology , Philadelphia, J. B. Lippincott Company, 1937. 91. Bigler, J. A., and Brennemann, J.: Sepsis with Leukopenia (Agranulocytosis) in Children , Am. J. Dis. Child. 40:515 ( (Sept.) ) 1930. 92. Jackson, H.: Agranulocytic Angina and Allied Conditions , Internat. Clin. 3:68 ( (Sept.) ) 1933. 93. Mosher.1 94. Beck.6b 95. Claus.26b 96. Claus.29 97. Beck.3a 98. Beck.9a 99. Claus.26b http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

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References (36)

Publisher
American Medical Association
Copyright
Copyright © 1943 American Medical Association. All Rights Reserved.
ISSN
0730-188X
DOI
10.1001/archinte.1943.00210060105008
Publisher site
See Article on Publisher Site

Abstract

Abstract Septicemia may be due to a number of causes. It is important to determine the exact cause in order that proper treatment may be instituted. The purpose of this paper is to call attention to one cause of septicemia often overlooked by the physician, namely, septic phlebitis of the internal jugular vein or of one of its branches.1 This condition is usually called postanginal sepsis or postanginal pyemia2 because it almost always follows an infection of the throat. Failure to recognize this dangerous disease has resulted in many fatalities. Early diagnosis and operation may save the life of the patient. Few reports of cases of postanginal sepsis are found in the American literature, although German and French observers have published many. Two cases are reported here to illustrate the clinical picture and the diagnosis of this entity. REPORT OF CASES Case 1. —D. W., a white girl of References 1. Mosher, H. P.: Submaxillary Fossa Approach to Deep Pus in the Neck , Tr. Am. Acad. Ophth. 34:19, 1929. 2. Abt, I. A.: Postanginal Sepsis , J. Pediat. 1:8 ( (July) ) 1932.Crossref 3. Waldapfel, R.: Die postanginöse Pyämie , Ztschr. f. Hals-, Nasen- u. Ohrenh. 23:178, 1929. 4. Burchardt, S.: Ein Beitrag zur Pathogenese der postanginösen Sepsis , Ztschr. f. Hals-, Nasen- u. Ohrenh. 23:97, 1929. 5. Beck, A. L.: Deep Neck Infection , Ann. Otol., Rhin. & Laryng. 48:940 ( (Dec.) ) 1939. 6. Hirsch, C.: Septicemia Following Tonsillitis , New York State J. Med. 35:767 ( (Aug. 1) ) 1935. 7. Reye, E.: Zur Pyämie nach Angina , Med. Welt 4:1791 ( (Dec. 13) ) 1930. 8. Mosher, H. P.: Deep Cervical Abscess and Thrombosis of the Internal Jugular Vein , Laryngoscope 30:365 ( (June) ) 1920. 9. Hall, C.: The Parapharyngeal Space , Ann. Otol., Rhin. & Laryng. 43:793 ( (Sept.) ) 1934. 10. Shapiro, S. L.: Deep Cervical Infection Following Tonsillectomy , Arch. Otolaryng. 11:201 ( (June) ) 1930. 11. Deering, W., and Brennemann, J.: Acute Abscess of the Throat , J. A. M. A. 118: 1171 ( (April 4) ) 1942. 12. Beck, A. L.: A Study of Twenty-Four Cases of Neck Infection , Tr. Am. Acad. Ophth. 37:342, 1932. 13. Haymann, L.: Erhebungen über die tonsillogene Sepsis , Ztschr. f. Hals-, Nasen- u. Ohrenh. 35:288, 1934. 14. Kissling, K.: Ueber postanginöse Sepsis , München. med. Wchnschr. 76:1163 ( (July 12) ) 1929. 15. Hall, C.: Sepsis Following Pharyngeal Infections , Ann. Otol., Rhin. & Laryng. 48:905 ( (Dec.) ) 1939. 16. Hirsch.3b 17. Reuben, M. S.: Postanginal Sepsis , Arch. Pediat. 52:152 ( (March) ) 1935. 18. Shapiro.5b 19. Beck, A. L.: Parapharyngeal Infections and Internal Jugular Vein Thrombosis: Diagnosis and Treatment , Laryngoscope 44:431 ( (June) ) 1934. 20. Reuben.8a 21. Waldapfel, R.: Post-Tonsillitis Pyemia , Tr. Am. Acad. Ophth. 33:291, 1928. 22. Hirsch.3b 23. Dixon, O. J., and Helwig, F. C.: Thrombophlebitis of the Internal Jugular Vein as a Complication of Tonsillitis , Ann. Otol., Rhin. & Laryng. 39:1137 ( (Dec.) ) 1930. 24. Joel, W.: Ueber die postanginöse Pyämie und ihre Verbreitungswege , Deutsche med. Wchnschr. 55:2133 ( (Dec. 20) ) 1929. 25. Hirsch.3b 26. Mosher.4 27. Hall.7b 28. Fraenkel, E.: Pyämie nach Angina , Deutsche med. Wchnschr. 52:93 ( (Jan. 15) ) 1926.Crossref 29. Waldapfel.10a 30. Hall.7b 31. Beck.9a 32. Waldapfel.10a 33. Knick: Die operative Heilung der tonsillären Sepsis , Ztschr. f. Hals-, Nasen- u. Ohrenh. 18:546, 1927-1928. 34. Waldapfel.10a 35. Dixon and Helwig.11a 36. Burchardt.2c 37. Beck.6b 38. Knick.14 39. Hirsch.3b 40. Mosher.4 41. Dixon and Helwig.11a 42. Bertelsmann, R.: Ueber Postanginöse Sepsis sive Bakterämie , Zentralbl. f. Chir. 54:642 ( (March 12) ) 1927. 43. Rubin, H.: Pyemia Following Acute Tonsillar Infections , Arch. Otolaryng 17:183 ( (Feb.) ) 1933.Crossref 44. Kissling.7a 45. Bertelsmann, R.: Postanginöse Sepsis und die Lymphbahnen , Zentralbl. f. Chir. 54: 1949 ( (July 30) ) 1927. 46. Beck.6b 47. Hall.7b 48. Kissling.7a 49. Dixon and Helwig.11a 50. Hirsch.3b 51. Beck.6b 52. Hall.7b 53. Hirsch.4b 54. Beck.9a 55. Matis, E. I.: Two Unusual Cases of Postanginal Sepsis , Ann. Otol., Rhin. & Laryng. 49:559 ( (June) ) 1940. 56. Salinger, S., and Pearlman, S. J.: Hemorrhage from Pharyngeal and Peritonsillar Abscess , Arch. Otolaryng. 18:464 ( (Oct.) ) 1933. 57. Kissling.7a 58. Dixon and Helwig.11a 59. Knick.14 60. Long, J. W.: Excision of Internal Jugular Vein for Streptococcic Thrombi Vein and Cavernous Sinus Causing Paralysis of Orbital Muscles , Surg., Gynec. & Obst. 14:86, 1912. 61. Claus, H.: Acht und zwanzig Fälle von Pyämie nach Angina , Ztschr. f. Hals-, Nasen- u. Ohrenh. 21:114, 1929. 62. Hirsch.3b 63. Rubin.18b 64. Stahl, R.: Zur Kenntis der Thrombophlebitis und Sepsis postanginosa , Deutsche med. Wchnschr. 53:186 ( (Jan. 28) ) 1927. 65. Fraenkel.12 66. Mlechlin, B., cited by Matis.23 67. Claus, H.: Bemerkungen zur Pyämie nach Angina , Ztschr. f. Hals-, Nasen- u. Ohrenh. 18:557, 1927. 68. Hall.7b 69. Claus.26b 70. Hall.7b 71. Claus.26b 72. Claus.29 73. Hall.7b 74. Beck.9a 75. Rubin.18b 76. Matis.23 77. Goodman, C.: Primary Jugular Thrombosis Due to Tonsil Infection , Ann. Otol., Rhin. & Laryng. 26:527, 1917. 78. Abt.2a 79. Beck.3a 80. Beck.6b 81. Stahl.27a 82. Hall.7b 83. Claus.29 84. Hirsch.3b 85. Hall.7b 86. Beck.9a 87. Claus.26b 88. White, P. D.: Heart Disease , ed. 2, New York, The Macmillan Company, 1931, p. 344. 89. Artuse, C., cited by Abt.2a 90. Kracke, R. R., and Garver, H. E.: Diseases of the Blood and Atlas of Hematology, with Clinical and Hematologic Descriptions of the Blood Diseases Including a Section on Technics and Terminology , Philadelphia, J. B. Lippincott Company, 1937. 91. Bigler, J. A., and Brennemann, J.: Sepsis with Leukopenia (Agranulocytosis) in Children , Am. J. Dis. Child. 40:515 ( (Sept.) ) 1930. 92. Jackson, H.: Agranulocytic Angina and Allied Conditions , Internat. Clin. 3:68 ( (Sept.) ) 1933. 93. Mosher.1 94. Beck.6b 95. Claus.26b 96. Claus.29 97. Beck.3a 98. Beck.9a 99. Claus.26b

Journal

Archives of Internal MedicineAmerican Medical Association

Published: Jun 1, 1943

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