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Possible Similarities Between the Fragile X and Asperger's Syndromes

Possible Similarities Between the Fragile X and Asperger's Syndromes Abstract Sir.—We read with interest the article these "Learning Disabilities and Attentional Problems in Boys with the Fragile X Syndrome" by Hagerman et al 1 in the July 1985 issue of AJDC. The authors described four boys with incontrovertible evidence of fragile X (fra[X]) chromosome but a higher than usual cognitive level of development, who also showed language difficulties and poor arithmetic skills with a relative strength in reading. All children also showed some atypical behavior, such as hand flapping, mouthing of objects, hand bitting, and a general pattern of distractibility and impulsiveness; one child showed fascination with spinning objects. The authors identified these children as showing a clinical picture of learning disabilities, but the behavioral, abormalities and the neurocognitive profile of these children would lead us to classify them instead as having Asperger's syndrome. In 1944, Asperger2d a syndrome that somewhat resembles Kane's8 picture of infantile autism. Curetly, we are investigating whether Asperger's8 syndrome is a variety of autism without mental retardation, or a separate syndrome. Wing4 resurrected the syndrome and slightly modified the diagnostic criteria on the basis of her experience with 34 cases. In this modified version, children with Asperger's syndrome snowed a delay References 1. HagermansR, Kemper s,bilities and attentional problems in boys with the fragile Xsyndrome . AJDC e fragile X syndrome. 2. Asperger H: Die 'PsychopiKinderP Nerv 1944;117:76-136. 3. Kanner L: Autistic disturbances of affective contact . Nervous Child 1943;2:217-250. 4. Wing L: Asperger's syndrome: A clinical account . Psychol Med http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Diseases of Children American Medical Association

Possible Similarities Between the Fragile X and Asperger's Syndromes

Possible Similarities Between the Fragile X and Asperger's Syndromes

Abstract

Abstract Sir.—We read with interest the article these "Learning Disabilities and Attentional Problems in Boys with the Fragile X Syndrome" by Hagerman et al 1 in the July 1985 issue of AJDC. The authors described four boys with incontrovertible evidence of fragile X (fra[X]) chromosome but a higher than usual cognitive level of development, who also showed language difficulties and poor arithmetic skills with a relative strength in reading. All children also showed some...
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Publisher
American Medical Association
Copyright
Copyright © 1987 American Medical Association. All Rights Reserved.
ISSN
0002-922X
DOI
10.1001/archpedi.1987.04460060019008
Publisher site
See Article on Publisher Site

Abstract

Abstract Sir.—We read with interest the article these "Learning Disabilities and Attentional Problems in Boys with the Fragile X Syndrome" by Hagerman et al 1 in the July 1985 issue of AJDC. The authors described four boys with incontrovertible evidence of fragile X (fra[X]) chromosome but a higher than usual cognitive level of development, who also showed language difficulties and poor arithmetic skills with a relative strength in reading. All children also showed some atypical behavior, such as hand flapping, mouthing of objects, hand bitting, and a general pattern of distractibility and impulsiveness; one child showed fascination with spinning objects. The authors identified these children as showing a clinical picture of learning disabilities, but the behavioral, abormalities and the neurocognitive profile of these children would lead us to classify them instead as having Asperger's syndrome. In 1944, Asperger2d a syndrome that somewhat resembles Kane's8 picture of infantile autism. Curetly, we are investigating whether Asperger's8 syndrome is a variety of autism without mental retardation, or a separate syndrome. Wing4 resurrected the syndrome and slightly modified the diagnostic criteria on the basis of her experience with 34 cases. In this modified version, children with Asperger's syndrome snowed a delay References 1. HagermansR, Kemper s,bilities and attentional problems in boys with the fragile Xsyndrome . AJDC e fragile X syndrome. 2. Asperger H: Die 'PsychopiKinderP Nerv 1944;117:76-136. 3. Kanner L: Autistic disturbances of affective contact . Nervous Child 1943;2:217-250. 4. Wing L: Asperger's syndrome: A clinical account . Psychol Med

Journal

American Journal of Diseases of ChildrenAmerican Medical Association

Published: Jun 1, 1987

References