Abstract IT IS AXIOMATIC that the retention of a sightless eye in adult life, especially one in which the interior structures cannot be visualized, is a hazard because of the possibility of the development of malignant melanoma under circumstances that preclude its early detection. In the case to be discussed below, a small pigmented choroidal tumor was discovered by chance in an enucleated phthisical eye. The growth was in close relation to a long ciliary nerve. Pigment was so abundant that few details of structure were visible, so that reduction of the pigmentation by bleaching was necessary. The cellular details so revealed suggested the advisability of discussion of the problem of establishing the benign or malignant nature of this particular lesion and of neoplasms in general. The presence of phthisis bulbi, which alone had been clinically apparent and which tended to mask the tumor on histologic examination, contributed collateral features of References 1. Dvorak-Theoblad, G.: Neurogenic Origin of Choroidal Sarcoma , Arch. Ophth. 18:971 ( (Dec.) ) 1937.Crossref 2. Reese, A. B.: Tumors of the Eye , New York, Paul B. Hoeber Inc., 1951, p. 219 3. Salzmann, M.: Anatomy and Histology of the Human Eyeball in the Normal State, Its Development and Senescence , authorized translation by E. V. H. Brown, Chicago, University of Chicago Press, 1912. 4. Allen, A. C.: A Reorientation of the Histogenesis and Clinical Significance of Cutaneous Nevi and Melanomas , Cancer 2:28, 1949.Crossref 5. Wilder, H. C., and Paul, E. V.: Malignant Melanoma of the Choroid and Ciliary Body, Mil , Surgeon 109:370, 1951. 6. Duke-Elder, W. S.: Text-Book of Ophthalmology , St. Louis, C. V. Mosby Company, 1949, Vol. 3, p. 2480. 7. Reese, A. B.: Tumors of the Eye , New York, Paul B. Hoeber, Inc., 1951, p. 222.
A.M.A. Archives of Ophthalmology – American Medical Association
Published: Jun 1, 1952
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