Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You and Your Team.

Learn More →

POSSIBLE MALIGNANT MELANOMA OF CHOROID: Pathologic Study of a Minute Tumor Discovered in an Enucleated Phthisical Eye

POSSIBLE MALIGNANT MELANOMA OF CHOROID: Pathologic Study of a Minute Tumor Discovered in an... Abstract IT IS AXIOMATIC that the retention of a sightless eye in adult life, especially one in which the interior structures cannot be visualized, is a hazard because of the possibility of the development of malignant melanoma under circumstances that preclude its early detection. In the case to be discussed below, a small pigmented choroidal tumor was discovered by chance in an enucleated phthisical eye. The growth was in close relation to a long ciliary nerve. Pigment was so abundant that few details of structure were visible, so that reduction of the pigmentation by bleaching was necessary. The cellular details so revealed suggested the advisability of discussion of the problem of establishing the benign or malignant nature of this particular lesion and of neoplasms in general. The presence of phthisis bulbi, which alone had been clinically apparent and which tended to mask the tumor on histologic examination, contributed collateral features of References 1. Dvorak-Theoblad, G.: Neurogenic Origin of Choroidal Sarcoma , Arch. Ophth. 18:971 ( (Dec.) ) 1937.Crossref 2. Reese, A. B.: Tumors of the Eye , New York, Paul B. Hoeber Inc., 1951, p. 219 3. Salzmann, M.: Anatomy and Histology of the Human Eyeball in the Normal State, Its Development and Senescence , authorized translation by E. V. H. Brown, Chicago, University of Chicago Press, 1912. 4. Allen, A. C.: A Reorientation of the Histogenesis and Clinical Significance of Cutaneous Nevi and Melanomas , Cancer 2:28, 1949.Crossref 5. Wilder, H. C., and Paul, E. V.: Malignant Melanoma of the Choroid and Ciliary Body, Mil , Surgeon 109:370, 1951. 6. Duke-Elder, W. S.: Text-Book of Ophthalmology , St. Louis, C. V. Mosby Company, 1949, Vol. 3, p. 2480. 7. Reese, A. B.: Tumors of the Eye , New York, Paul B. Hoeber, Inc., 1951, p. 222. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Ophthalmology American Medical Association

POSSIBLE MALIGNANT MELANOMA OF CHOROID: Pathologic Study of a Minute Tumor Discovered in an Enucleated Phthisical Eye

A.M.A. Archives of Ophthalmology , Volume 47 (6) – Jun 1, 1952

Loading next page...
 
/lp/american-medical-association/possible-malignant-melanoma-of-choroid-pathologic-study-of-a-minute-Calp0RKR8T
Publisher
American Medical Association
Copyright
Copyright © 1952 American Medical Association. All Rights Reserved.
ISSN
0096-6339
DOI
10.1001/archopht.1952.01700030753005
Publisher site
See Article on Publisher Site

Abstract

Abstract IT IS AXIOMATIC that the retention of a sightless eye in adult life, especially one in which the interior structures cannot be visualized, is a hazard because of the possibility of the development of malignant melanoma under circumstances that preclude its early detection. In the case to be discussed below, a small pigmented choroidal tumor was discovered by chance in an enucleated phthisical eye. The growth was in close relation to a long ciliary nerve. Pigment was so abundant that few details of structure were visible, so that reduction of the pigmentation by bleaching was necessary. The cellular details so revealed suggested the advisability of discussion of the problem of establishing the benign or malignant nature of this particular lesion and of neoplasms in general. The presence of phthisis bulbi, which alone had been clinically apparent and which tended to mask the tumor on histologic examination, contributed collateral features of References 1. Dvorak-Theoblad, G.: Neurogenic Origin of Choroidal Sarcoma , Arch. Ophth. 18:971 ( (Dec.) ) 1937.Crossref 2. Reese, A. B.: Tumors of the Eye , New York, Paul B. Hoeber Inc., 1951, p. 219 3. Salzmann, M.: Anatomy and Histology of the Human Eyeball in the Normal State, Its Development and Senescence , authorized translation by E. V. H. Brown, Chicago, University of Chicago Press, 1912. 4. Allen, A. C.: A Reorientation of the Histogenesis and Clinical Significance of Cutaneous Nevi and Melanomas , Cancer 2:28, 1949.Crossref 5. Wilder, H. C., and Paul, E. V.: Malignant Melanoma of the Choroid and Ciliary Body, Mil , Surgeon 109:370, 1951. 6. Duke-Elder, W. S.: Text-Book of Ophthalmology , St. Louis, C. V. Mosby Company, 1949, Vol. 3, p. 2480. 7. Reese, A. B.: Tumors of the Eye , New York, Paul B. Hoeber, Inc., 1951, p. 222.

Journal

A.M.A. Archives of OphthalmologyAmerican Medical Association

Published: Jun 1, 1952

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$499/year

Save searches from
Google Scholar,
PubMed

Create folders to
organize your research

Export folders, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month