Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Positivity of the Methylene Blue Test in Xanthomatosis

Positivity of the Methylene Blue Test in Xanthomatosis Abstract In two previous papers1,2 published in the International Journal of Leprosy, one of us (J. Convit) reported the work carried out in collaboration with C. Sisirucá, P. Lapenta, and S. Mendoza with the methylene blue test in leprosy patients with special emphasis on the reaction in borderline cases. It was observed that in these cases intravenous injections of a 1% solution of the dye stained the lepromatous areas of the lesions, but left the tuberculoid parts unaffected. This observation was amply confirmed by the histopathological study of skin specimens. When the dye was administered in a similar manner to patients with indeterminate and tuberculoid leprosy no retention was observed. The daily doses which began with 2 to 3 cc were stepped up gradually to 10 to 15 cc until a total of 100 had been administered. The patients tolerated the dye well and showed no appreciable toxic effect. We References 1. Convit, J.; Sisirucá C.; and Lapenta, P.: Some Observations on Borderline Leprosy , Int J Leprosy 24:354-381, 1956. 2. Convit, J.; Lapenta, P.; and Mendoza, S. J.: The Methylene Blue Test in Leprosy , Int J Leprosy 28:233-238, 1960. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Positivity of the Methylene Blue Test in Xanthomatosis

Archives of Dermatology , Volume 88 (3) – Sep 1, 1963

Positivity of the Methylene Blue Test in Xanthomatosis

Abstract

Abstract In two previous papers1,2 published in the International Journal of Leprosy, one of us (J. Convit) reported the work carried out in collaboration with C. Sisirucá, P. Lapenta, and S. Mendoza with the methylene blue test in leprosy patients with special emphasis on the reaction in borderline cases. It was observed that in these cases intravenous injections of a 1% solution of the dye stained the lepromatous areas of the lesions, but left the tuberculoid parts unaffected. This...
Loading next page...
 
/lp/american-medical-association/positivity-of-the-methylene-blue-test-in-xanthomatosis-qpPFbP7wV0
Publisher
American Medical Association
Copyright
Copyright © 1963 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1963.01590210108017
Publisher site
See Article on Publisher Site

Abstract

Abstract In two previous papers1,2 published in the International Journal of Leprosy, one of us (J. Convit) reported the work carried out in collaboration with C. Sisirucá, P. Lapenta, and S. Mendoza with the methylene blue test in leprosy patients with special emphasis on the reaction in borderline cases. It was observed that in these cases intravenous injections of a 1% solution of the dye stained the lepromatous areas of the lesions, but left the tuberculoid parts unaffected. This observation was amply confirmed by the histopathological study of skin specimens. When the dye was administered in a similar manner to patients with indeterminate and tuberculoid leprosy no retention was observed. The daily doses which began with 2 to 3 cc were stepped up gradually to 10 to 15 cc until a total of 100 had been administered. The patients tolerated the dye well and showed no appreciable toxic effect. We References 1. Convit, J.; Sisirucá C.; and Lapenta, P.: Some Observations on Borderline Leprosy , Int J Leprosy 24:354-381, 1956. 2. Convit, J.; Lapenta, P.; and Mendoza, S. J.: The Methylene Blue Test in Leprosy , Int J Leprosy 28:233-238, 1960.

Journal

Archives of DermatologyAmerican Medical Association

Published: Sep 1, 1963

References