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Portal Hypertension in Secondary Biliary Cirrhosis

Portal Hypertension in Secondary Biliary Cirrhosis Abstract ALTHOUGH cirrhosis is a relatively uncommon complication of extrahepatic biliary obstruction,1 portal hypertension develops in a significant number of patients who have secondary biliary cirrhosis. Review of the records of 160 patients seen at the Mayo Clinic between January 1950, and July 1965, who were considered to have cirrhosis caused by extrahepatic biliary obstruction revealed 37 patients with demonstrable esophageal varices. This 23% incidence of portal hypertension complicating secondary cirrhosis is only approximate because the diagnosis of secondary cirrhosis was not verified anatomically, or histologically in all of the 160 cases, and because portal hypertension undoubtedly existed in many instances in which varices were not demonstrable. However, it is similar to the incidence reported by Sedgwick and associates,2 and by our medical colleagues3 in their review based on more critical diagnostic criteria. Surgical management of this combination of disorders may be complicated by: (1) the presence of adhesions References 1. Gibson, W.R., and Robertson, H.E.: So-Called Biliary Cirrhosis , Arch Path 28:37-48 ( (July) ) 1939. 2. Sedgwick, C.E.; Poulantzas, J.K.; and Kune, G.A.: Management of Portal Hypertension Secondary to Bile Duct Strictures: Review of 18 Cases With Splenorenal Shunt , Ann Surg 163:949-953 ( (June) ) 1966.Crossref 3. Scobie, B.A., and Summerskill, W.H.J.: Hepatic Cirrhosis Secondary to Obstruction of the Biliary System , Amer J Dig Dis 10:135-146 ( (Feb) ) 1965.Crossref 4. Adson, M.A.: Emergency Portal-Systemic Shunts , Surg Clin N Amer 47:887-898 ( (Aug) ) 1967. 5. Hallenbeck, G.A., et al: Results After Portal-Systemic Shunts in 120 Patients With Cirrhosis of the Liver , Surg Gynec Obstet 116:435-442 ( (April) ) 1963. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Surgery American Medical Association

Portal Hypertension in Secondary Biliary Cirrhosis

Archives of Surgery , Volume 96 (4) – Apr 1, 1968

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Publisher
American Medical Association
Copyright
Copyright © 1968 American Medical Association. All Rights Reserved.
ISSN
0004-0010
eISSN
1538-3644
DOI
10.1001/archsurg.1968.01330220120020
Publisher site
See Article on Publisher Site

Abstract

Abstract ALTHOUGH cirrhosis is a relatively uncommon complication of extrahepatic biliary obstruction,1 portal hypertension develops in a significant number of patients who have secondary biliary cirrhosis. Review of the records of 160 patients seen at the Mayo Clinic between January 1950, and July 1965, who were considered to have cirrhosis caused by extrahepatic biliary obstruction revealed 37 patients with demonstrable esophageal varices. This 23% incidence of portal hypertension complicating secondary cirrhosis is only approximate because the diagnosis of secondary cirrhosis was not verified anatomically, or histologically in all of the 160 cases, and because portal hypertension undoubtedly existed in many instances in which varices were not demonstrable. However, it is similar to the incidence reported by Sedgwick and associates,2 and by our medical colleagues3 in their review based on more critical diagnostic criteria. Surgical management of this combination of disorders may be complicated by: (1) the presence of adhesions References 1. Gibson, W.R., and Robertson, H.E.: So-Called Biliary Cirrhosis , Arch Path 28:37-48 ( (July) ) 1939. 2. Sedgwick, C.E.; Poulantzas, J.K.; and Kune, G.A.: Management of Portal Hypertension Secondary to Bile Duct Strictures: Review of 18 Cases With Splenorenal Shunt , Ann Surg 163:949-953 ( (June) ) 1966.Crossref 3. Scobie, B.A., and Summerskill, W.H.J.: Hepatic Cirrhosis Secondary to Obstruction of the Biliary System , Amer J Dig Dis 10:135-146 ( (Feb) ) 1965.Crossref 4. Adson, M.A.: Emergency Portal-Systemic Shunts , Surg Clin N Amer 47:887-898 ( (Aug) ) 1967. 5. Hallenbeck, G.A., et al: Results After Portal-Systemic Shunts in 120 Patients With Cirrhosis of the Liver , Surg Gynec Obstet 116:435-442 ( (April) ) 1963.

Journal

Archives of SurgeryAmerican Medical Association

Published: Apr 1, 1968

References