Abstract Introduction FIBROUS dysplasia may be manifested by involvement of only one bone (monostotic), more than one (polyostotic), or by McCune-Albright syndrome. The original descriptions of McCune-Albright syndrome in this country consisted of café au lait spots, polyostotic fibrous dysplasia, and sexual precocity.1-3 There are a number of good reviews describing the clinical, radiological, and pathological aspects of this syndrome to which the reader is referred.1-8 In order to make this diagnosis, the classical triad should be present although some investigators5,6 do not consider sexual precocity to be necessary. Lichtenstein,9 in 1938 and again in 1942 in collaboration with Jaffe,10 stressed the pathological aspects of the bony abnormalities of the disease and termed the true nature of these as a fibrous dysplasia.A 6-year-old Negro boy was admitted to the Pediatric Service of the Boston City Hospital, presenting with polyostotic fibrous dysplasia and café au lait References 1. McCune, D. J.: Osteitis Fibrosa Cystica: Case of Nine Year Old Girl Who Also Exhibits Precocious Puberty, Multiple Pigmentation of Skin and Hyperthyroidism: Transactions of Society for Pediatric Research , Amer J Dis Child 52:743-747, 1936. 2. McCune, D. J., and Bruch, H.: Osteodystrophia Fibrosa: Report of Case in Which Condition Was Combined With Precocious Puberty, Pathologic Pigmentation of Skin and Hyperthyroidism, With Review of Literature , Amer J Dis Child 54:806-848, 1937.Crossref 3. Albright, F., et al: Syndrome Characterized by Osteitis Fibrosa Disseminata, Areas of Pigmentation and Endocrine Dysfunction With Precocious Puberty in Females , New Eng J Med 216:727-746, 1937.Crossref 4. Albright, F.: Polyostotic Fibrous Dysplasia: Defense of Entity , J Clin Endocr 7:307-324, 1947.Crossref 5. Pritchard, J. E.: Fibrous Dysplasia of Bones , Amer J Med Sci 222:313-332, 1951.Crossref 6. Falconer, M. A., and Cope, C. L.: Fibrous Dysplasia of Bone With Endocrine Disorders and Cutaneous Pigmentation (Albright's Disease) , Quart J Med 35:121-154, 1942. 7. Harris, W. H.; Dudley, H. R., Jr.; and Barry, R. J.: Natural History of Fibrous Dysplasia , J Bone Joint Surg 44-A:207-233, 1962. 8. Benedict, P. H.: Endocrine Features in Albright's Syndrome (Fibrous Dysplasia of Bone) , Metabolism 11:30-45, 1962. 9. Lichtenstein, L.: Polyostotic Fibrous Dysplasia , Arch Surg 36:874-898, 1938.Crossref 10. Lichtenstein, L., and Jaffe, H. L.: Fibrous Dysplasia of Bone: Condition Affecting One, Several or Many Bones, Graver Cases of Which May Present Abnormal Pigmentation of Skin, Premature Sexual Development, Hyperthyroidism, or Still Other Skeletal Abnormalities , Arch Path 33:777-816, 1942. 11. Caldwell, G. A., and Broderick, T. F., Jr.: Polyostotic Fibrous Dysplasia in One of Negro Twin Girls , Ann Intern Med 27:114-126, 1947.Crossref 12. Fries, J. W.: Roentgen Features of Fibrous Dysplasia of Skull and Facial Bones , Amer J Roentgen 77:71-88, 1957. 13. Schlumberger, H. G.: Fibrous Dysplasia of Single Bones (Monostotic Fibrous Dysplasia) , Milit Surg 99:504-527, 1946. 14. Bogart, F. B., and Imler, A. E.: Fibrous Dysplasia of Bone , Amer J Roentgen 58:478-485, 1947. 15. Towson, C. E.: Monostotic Fibrous Dysplasia of Mastoid and Temporal Bone , Arch Otolaryng 52:709-724, 1950.Crossref 16. Reed, R. J.: Fibrous Dysplasia of Bone , Arch Path 75:480-495, 1963.
American Journal of Diseases of Children – American Medical Association
Published: Jun 1, 1965