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Polymyositis With Infiltration by Lymphoid Follicles

Polymyositis With Infiltration by Lymphoid Follicles Abstract • The clinical and histopathological features of a case of polymyositis were studied. The biopsy specimen displayed muscular infiltration, with clear germinalcenter lymphoid follicles. Gastric cancer was discovered 18 months after the appearance of myopathic signs. Therapy with corticosteroids, other immunosuppressive drugs, and then the ablation of the gastric tumor did not stop the progression of the myopathy. References 1. Devere R, Bradley WG: Polymyositis: Its presentation, mobidity and mortality . Brain 1975;98:637-666.Crossref 2. Engel WK, Askanas V: Remote effects of focal cancer on the neuromuscular system . Adv Neurol 1976;15:119-147. 3. Mack KW, Wilgram GF: Cutaneous lymphoplasia with giant follicles . Arch Dermatol 1966;94:749-756.Crossref 4. Pearson CM: Polymyositis and related discorders , in Walton JN (ed): Disorders of Voluntary Muscle , ed 2. Boston, Little Brown & Co, 1969, pp 501-539. 5. Barnes BE, Mawr B: Dermatomyositis and malignancy . Ann Intern Med 1976;84:68-76.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Neurology American Medical Association

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Publisher
American Medical Association
Copyright
Copyright © 1981 American Medical Association. All Rights Reserved.
ISSN
0003-9942
eISSN
1538-3687
DOI
10.1001/archneur.1981.00510120077014
Publisher site
See Article on Publisher Site

Abstract

Abstract • The clinical and histopathological features of a case of polymyositis were studied. The biopsy specimen displayed muscular infiltration, with clear germinalcenter lymphoid follicles. Gastric cancer was discovered 18 months after the appearance of myopathic signs. Therapy with corticosteroids, other immunosuppressive drugs, and then the ablation of the gastric tumor did not stop the progression of the myopathy. References 1. Devere R, Bradley WG: Polymyositis: Its presentation, mobidity and mortality . Brain 1975;98:637-666.Crossref 2. Engel WK, Askanas V: Remote effects of focal cancer on the neuromuscular system . Adv Neurol 1976;15:119-147. 3. Mack KW, Wilgram GF: Cutaneous lymphoplasia with giant follicles . Arch Dermatol 1966;94:749-756.Crossref 4. Pearson CM: Polymyositis and related discorders , in Walton JN (ed): Disorders of Voluntary Muscle , ed 2. Boston, Little Brown & Co, 1969, pp 501-539. 5. Barnes BE, Mawr B: Dermatomyositis and malignancy . Ann Intern Med 1976;84:68-76.Crossref

Journal

Archives of NeurologyAmerican Medical Association

Published: Dec 1, 1981

References