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Polycythemia Vera in the Childbearing Age

Polycythemia Vera in the Childbearing Age Abstract POLYCYTHEMIA VERA is a medical disorder that is recognized infrequently in young women. However, it does occur and it should be regarded as a significant cause of complications. Only three patients with polycythemia vera coinciding with pregnancy have been reported,1-3 and in these reports there was no specific consideration of the problems of infertility, fetal wastage, and preeclampsia. At Wilford Hall USAF Hospital five women in the childbearing age have been found to have polycythemia vera. In two of these cases the diagnosis was made during pregnancy; the authors believe this to be the first time it was ever diagnosed during pregnancy. This report illustrates the problems of the five women with respect to infertility and complications of pregnancy. Report of Cases CASE 1. —An 18-year-old white woman, P 00-0-0, was presented at 20 weeks' gestation with symptoms of chronic fatigue, nausea, and occasional emesis. Physical examination was within References 1. Erf, L.A.: "Radioactive Phosphorus in the Treatment of Primary Polycythemia (Vera) , in L.M. Tocantins (ed.): Progress in Hematology , New York: Grune & Stratton, Inc., 1956, pp 153-165. 2. Hochman, A., and Stein, J.A.: Polycythemia and Pregnancy: Report of a Case , Obstet Gynec 18:230-235, 1961. 3. Ruch, W.A., and Klein, R.L.: Polycythemia Vera and Pregnancy: Report of a Case , Obstet Gynec 23:107-111, 1964. 4. Modan, B.: Polycythemia: A Review of Epidemiological and Clinical Aspects , J Chronic Dis 18:605-645, 1965.Crossref 5. Moore, F.D., et al: The Body Cell Mass and Its Supporting Environment , Philadelphia: W. B. Saunders Co., 1963. 6. Leavell, B.S., and Thorup, O.A., Jr.: Fundamentals of Clinical Hematology , ed 2, Philadelphia: W. B. Saunders Co., 1966, pp 261-269. 7. Wintrobe, M.M.: Clinical Hematology , ed 5, Philadelphia: Lea & Febiger, Publishers, 1961, pp 793-815. 8. Osgood, E.E.: Polycythemia Vera: Age Relationships and Survival , Blood 26:243-256, 1965. 9. Ruch, W.A., Jr.: Letter to OB-Gyn Collected Letters of The International Correspondence Society of Obstetricians and Gynecologists , series 7, March 15, 1966, Lakeland, Fla: OB-Gyn Letters, Inc., 1966, p 46. 10. Modan, B., and Lilienfeld, A.M.: Polycythemia Vera and Leukemia—the Role of Radiation Treatment: A Study of 1222 Patients , Medicine 44: 305-344, 1965.Crossref 11. Modan, B.: Radiophosphorus Therapy in Polycythemia , Blood 26:383-386, 1965. 12. Lawrence, J.H.: Polycythemia , monograph in Modern Medical Monographs, vol 13, New York: Grune & Stratton, Inc., 1955. 13. Wasserman, L.R., and Gilbert, H.S.: Surgery in Polycythemia Vera , New Eng J Med 269:1226-1230, 1963.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

Polycythemia Vera in the Childbearing Age

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Publisher
American Medical Association
Copyright
Copyright © 1967 American Medical Association. All Rights Reserved.
ISSN
0003-9926
eISSN
1538-3679
DOI
10.1001/archinte.1967.00300050053008
Publisher site
See Article on Publisher Site

Abstract

Abstract POLYCYTHEMIA VERA is a medical disorder that is recognized infrequently in young women. However, it does occur and it should be regarded as a significant cause of complications. Only three patients with polycythemia vera coinciding with pregnancy have been reported,1-3 and in these reports there was no specific consideration of the problems of infertility, fetal wastage, and preeclampsia. At Wilford Hall USAF Hospital five women in the childbearing age have been found to have polycythemia vera. In two of these cases the diagnosis was made during pregnancy; the authors believe this to be the first time it was ever diagnosed during pregnancy. This report illustrates the problems of the five women with respect to infertility and complications of pregnancy. Report of Cases CASE 1. —An 18-year-old white woman, P 00-0-0, was presented at 20 weeks' gestation with symptoms of chronic fatigue, nausea, and occasional emesis. Physical examination was within References 1. Erf, L.A.: "Radioactive Phosphorus in the Treatment of Primary Polycythemia (Vera) , in L.M. Tocantins (ed.): Progress in Hematology , New York: Grune & Stratton, Inc., 1956, pp 153-165. 2. Hochman, A., and Stein, J.A.: Polycythemia and Pregnancy: Report of a Case , Obstet Gynec 18:230-235, 1961. 3. Ruch, W.A., and Klein, R.L.: Polycythemia Vera and Pregnancy: Report of a Case , Obstet Gynec 23:107-111, 1964. 4. Modan, B.: Polycythemia: A Review of Epidemiological and Clinical Aspects , J Chronic Dis 18:605-645, 1965.Crossref 5. Moore, F.D., et al: The Body Cell Mass and Its Supporting Environment , Philadelphia: W. B. Saunders Co., 1963. 6. Leavell, B.S., and Thorup, O.A., Jr.: Fundamentals of Clinical Hematology , ed 2, Philadelphia: W. B. Saunders Co., 1966, pp 261-269. 7. Wintrobe, M.M.: Clinical Hematology , ed 5, Philadelphia: Lea & Febiger, Publishers, 1961, pp 793-815. 8. Osgood, E.E.: Polycythemia Vera: Age Relationships and Survival , Blood 26:243-256, 1965. 9. Ruch, W.A., Jr.: Letter to OB-Gyn Collected Letters of The International Correspondence Society of Obstetricians and Gynecologists , series 7, March 15, 1966, Lakeland, Fla: OB-Gyn Letters, Inc., 1966, p 46. 10. Modan, B., and Lilienfeld, A.M.: Polycythemia Vera and Leukemia—the Role of Radiation Treatment: A Study of 1222 Patients , Medicine 44: 305-344, 1965.Crossref 11. Modan, B.: Radiophosphorus Therapy in Polycythemia , Blood 26:383-386, 1965. 12. Lawrence, J.H.: Polycythemia , monograph in Modern Medical Monographs, vol 13, New York: Grune & Stratton, Inc., 1955. 13. Wasserman, L.R., and Gilbert, H.S.: Surgery in Polycythemia Vera , New Eng J Med 269:1226-1230, 1963.Crossref

Journal

Archives of Internal MedicineAmerican Medical Association

Published: Dec 1, 1967

References