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Polio Surge

Polio Surge Sparked by concerns about a surge of poliomyelitis cases in Nigeria caused by a vaccine-derived strain of type 2 poliovirus, health officials stepped up efforts to curb its spread, according to the Global Polio Vaccine Initiative (http://www.polioeradication.org/content/general/current_monthly_sitrep.asp). Although type 2 wild poliovirus (1 of the 3 serotypes of wild poliovirus) had been eradicated in 1999, it reemerged a few years ago when weakened type 2 virus in oral polio vaccine mutated. For reasons not well understood, circulating vaccine-derived poliovirus began spreading more aggressively in 2009. By late July, 124 cases of paralysis caused by vaccine-derived virus had been confirmed for 2009, more than 4 times the number of cases confirmed in July 2008. Nigeria held nationwide immunization days in early August using trivalent oral polio vaccine in order to tackle both the vaccine-derived type 2 virus and an increase in type 3 cases. However, violence in northern and eastern Nigeria resulted in some states postponing their immunization activities. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Polio Surge

JAMA , Volume 302 (11) – Sep 16, 2009

Polio Surge

Abstract

Sparked by concerns about a surge of poliomyelitis cases in Nigeria caused by a vaccine-derived strain of type 2 poliovirus, health officials stepped up efforts to curb its spread, according to the Global Polio Vaccine Initiative (http://www.polioeradication.org/content/general/current_monthly_sitrep.asp). Although type 2 wild poliovirus (1 of the 3 serotypes of wild poliovirus) had been eradicated in 1999, it reemerged a few years ago when weakened type 2 virus in oral polio vaccine mutated....
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Publisher
American Medical Association
Copyright
Copyright © 2009 American Medical Association. All Rights Reserved.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2009.1337
Publisher site
See Article on Publisher Site

Abstract

Sparked by concerns about a surge of poliomyelitis cases in Nigeria caused by a vaccine-derived strain of type 2 poliovirus, health officials stepped up efforts to curb its spread, according to the Global Polio Vaccine Initiative (http://www.polioeradication.org/content/general/current_monthly_sitrep.asp). Although type 2 wild poliovirus (1 of the 3 serotypes of wild poliovirus) had been eradicated in 1999, it reemerged a few years ago when weakened type 2 virus in oral polio vaccine mutated. For reasons not well understood, circulating vaccine-derived poliovirus began spreading more aggressively in 2009. By late July, 124 cases of paralysis caused by vaccine-derived virus had been confirmed for 2009, more than 4 times the number of cases confirmed in July 2008. Nigeria held nationwide immunization days in early August using trivalent oral polio vaccine in order to tackle both the vaccine-derived type 2 virus and an increase in type 3 cases. However, violence in northern and eastern Nigeria resulted in some states postponing their immunization activities.

Journal

JAMAAmerican Medical Association

Published: Sep 16, 2009

Keywords: poliomyelitis

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