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Pneumococcic Meningitis

Pneumococcic Meningitis COMMENTARY Complete Recovery of a 6-Month-Old Infant Treated With Penicillin BRAHAM M. LITVAK, TREATING ACCESS TO PENICILLIN director of pediat- PNEUMOCOCCAL MENINGITIS BEFORE PENICILLIN rics at Beth-El Hos- Reports that gram-positive organ- pital in Brooklyn, isms such as the pneumococcus re- New York, and his Eminent pediatrician Luther Em- sponded to penicillin excited phy- colleagues Emanuel Appelbaum and mett Holt observed in the first is- sicians, who then became anxious to Morton Greene could scarcely be- sue of AJDC in 1911 that the diag- try it in clinical practice. However, lieve their eyes in early November nosis of pneumococcal meningitis obtaining penicillin proved diffi- 4(p36) 1943 at the response of a 6-month- was “almost invariably fatal.” As cult before 1945 because the mili- old “moribund” infant to the new pediatrician and infectious disease tary controlled most of the supply drug penicillin. They character- researcher Hattie Alexander de- during World War II. By March ized the infant’s “dramatic” recov- tailed in AJDC in 1943, until the ad- 1942, only enough penicillin had ery from highly fatal “pneumococ- vent of sulfonamide therapy in the been produced by American com- cic” meningitis as “little short of late 1930s, standard treatment for panies http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Pediatrics American Medical Association

Pneumococcic Meningitis

JAMA Pediatrics , Volume 165 (5) – May 1, 2011

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Publisher
American Medical Association
Copyright
Copyright 2011 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6203
eISSN
2168-6211
DOI
10.1001/archpediatrics.2011.37
pmid
21536951
Publisher site
See Article on Publisher Site

Abstract

COMMENTARY Complete Recovery of a 6-Month-Old Infant Treated With Penicillin BRAHAM M. LITVAK, TREATING ACCESS TO PENICILLIN director of pediat- PNEUMOCOCCAL MENINGITIS BEFORE PENICILLIN rics at Beth-El Hos- Reports that gram-positive organ- pital in Brooklyn, isms such as the pneumococcus re- New York, and his Eminent pediatrician Luther Em- sponded to penicillin excited phy- colleagues Emanuel Appelbaum and mett Holt observed in the first is- sicians, who then became anxious to Morton Greene could scarcely be- sue of AJDC in 1911 that the diag- try it in clinical practice. However, lieve their eyes in early November nosis of pneumococcal meningitis obtaining penicillin proved diffi- 4(p36) 1943 at the response of a 6-month- was “almost invariably fatal.” As cult before 1945 because the mili- old “moribund” infant to the new pediatrician and infectious disease tary controlled most of the supply drug penicillin. They character- researcher Hattie Alexander de- during World War II. By March ized the infant’s “dramatic” recov- tailed in AJDC in 1943, until the ad- 1942, only enough penicillin had ery from highly fatal “pneumococ- vent of sulfonamide therapy in the been produced by American com- cic” meningitis as “little short of late 1930s, standard treatment for panies

Journal

JAMA PediatricsAmerican Medical Association

Published: May 1, 2011

References

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