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Platelet-Rich Plasma Injection for Chronic Achilles Tendinopathy

Platelet-Rich Plasma Injection for Chronic Achilles Tendinopathy PRELIMINARY COMMUNICATION Platelet-Rich Plasma Injection for Chronic Achilles Tendinopathy A Randomized Controlled Trial Robert J. de Vos, MD Context Tendon disorders comprise 30% to 50% of all activity-related injuries; chronic Adam Weir, MBBS degenerative tendon disorders (tendinopathy) occur frequently and are difficult to treat. Tendon regeneration might be improved by injecting platelet-rich plasma (PRP), an in- Hans T. M. van Schie, DVM, PhD creasingly used treatment for releasing growth factors into the degenerative tendon. Sita M. A. Bierma-Zeinstra, PhD Objective To examine whether a PRP injection would improve outcome in chronic Jan A. N. Verhaar, MD, PhD midportion Achilles tendinopathy. Harrie Weinans, PhD Design, Setting, and Patients A stratified, block-randomized, double-blind, placebo- controlled trial at a single center (The Hague Medical Center, Leidschendam, the Neth- Johannes L. Tol, MD, PhD erlands) of 54 randomized patients aged 18 to 70 years with chronic tendinopathy 2 VERUSE INJURY OF THE ACHIL- to 7 cm above the Achilles tendon insertion. The trial was conducted between August 28, 2008, and January 29, 2009, with follow-up until July 16, 2009. les tendon is a frequent prob- lem that often affects sport Intervention Eccentric exercises (usual care) with either a PRP injection (PRP group) Oparticipants http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

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Publisher
American Medical Association
Copyright
Copyright 2010 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2009.1986
pmid
20068208
Publisher site
See Article on Publisher Site

Abstract

PRELIMINARY COMMUNICATION Platelet-Rich Plasma Injection for Chronic Achilles Tendinopathy A Randomized Controlled Trial Robert J. de Vos, MD Context Tendon disorders comprise 30% to 50% of all activity-related injuries; chronic Adam Weir, MBBS degenerative tendon disorders (tendinopathy) occur frequently and are difficult to treat. Tendon regeneration might be improved by injecting platelet-rich plasma (PRP), an in- Hans T. M. van Schie, DVM, PhD creasingly used treatment for releasing growth factors into the degenerative tendon. Sita M. A. Bierma-Zeinstra, PhD Objective To examine whether a PRP injection would improve outcome in chronic Jan A. N. Verhaar, MD, PhD midportion Achilles tendinopathy. Harrie Weinans, PhD Design, Setting, and Patients A stratified, block-randomized, double-blind, placebo- controlled trial at a single center (The Hague Medical Center, Leidschendam, the Neth- Johannes L. Tol, MD, PhD erlands) of 54 randomized patients aged 18 to 70 years with chronic tendinopathy 2 VERUSE INJURY OF THE ACHIL- to 7 cm above the Achilles tendon insertion. The trial was conducted between August 28, 2008, and January 29, 2009, with follow-up until July 16, 2009. les tendon is a frequent prob- lem that often affects sport Intervention Eccentric exercises (usual care) with either a PRP injection (PRP group) Oparticipants

Journal

JAMAAmerican Medical Association

Published: Jan 13, 2010

References