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PLASMA CELL MYELOMA OF THE PHARYNX AND CERVICAL REGION WITHOUT SKELETAL INVOLVEMENT

PLASMA CELL MYELOMA OF THE PHARYNX AND CERVICAL REGION WITHOUT SKELETAL INVOLVEMENT Abstract Multiple myeloma essentially represents a malignant neoplastic disease of the bone marrow which rarely, if ever, metastasizes. We are reporting a case of plasma cell myeloma of the pharynx and cervical region without apparent skeletal involvement. REPORT OF CASE A man, aged 60, came to the clinic on April 30, 1930. He had first noticed a swelling in his throat and in the right side of his neck two or three months previously. There was slight difficulty in swallowing and breathing but no pain. General examination gave essentially negative results, except for obesity, chronic myocardial degeneration and a moderate degree of hypertension. Examination of the throat revealed an ulcerated, polypoid mass about 3 by 2.5 cm. in the right side of the pharynx which apparently originated in the tonsil. There was also a mass in the right upper cervical region 4 cm. in diameter. Roentgenograms of the References 1. Ewing, James: Neoplastic Diseases , ed. 3, Philadelphia, W. B. Saunders Company, 1928, p. 321. 2. Jackson, Henry, Jr.; Parker, Frederic, Jr., and Bethea, J. M.: Studies of Diseases of the Lymphoid and Myeloid Tissues: II. Plasmatocytomata and Their Relation to Multiple Myelomata , Am. J. M. Sc. 181:169 ( (Feb.) ) 1931.Crossref 3. MacCallum, W. G.: A Text-Book of Pathology , ed. 4, Philadelphia, W. B. Saunders Company, 1928, p. 838. 4. Ribbert, Hugo: Ueber das Myelom , Centralbl. f. allg. Path. u. path. Anat. 15:337 ( (May 15) ) 1904. 5. Pepper, O. H. P., and Pearce, R. M.: Myeloma with Metastasis to Liver and Spleen , J. M. Research 37:171 ( (Sept.) ) 1917. 6. Meyerding, H. W.: Multiple Myeloma , Radiology 5:132 ( (Aug.) ) 1925. 7. Kolodny, Anatole: Bone Sarcoma , Surg., Gynec. & Obst. 44:155 and 162, 1927. 8. Geschickter, C. F., and Copeland, M. M.: Multiple Myeloma , Arch. Surg. 16:807 ( (April) ) 1928. 9. Schütz, Hans: Fall von multiplem Myelom mit Bence-Jones'scher Albuminurie und Metastase (beziehungsweise homologer autochthoner Neubildung) in der rechten Tonsille , Deutsches Arch. f. klin. Med. 113:441 ( (March 10) ) 1914. 10. Anders, J. M., and Boston, L. N.: Bence-Jones Albumosuria, with Report of Three Cases , Lancet 1:93 ( (Jan. 10) ) 1903. 11. Beck, J. C.: Some Uncommon Types of Neoplasms About the Head , Laryngoscope 40:511 ( (July) ) 1930. 12. Kaufmann, Eduard: Pathology , Philadelphia, P. Blakiston's Son & Co., 1929, vol. 1, pp. 272 and 625; vol. 2, pp. 1217 and 1221. 13. Kusunoki and Frank: Ueber ein plasmazelluläres Granulom unter dem klinischen Bilde von Lymphomen der Halslymphdrüsen und geschwulstartigen Knoten in der Nasenschleimhaut , Virchows Arch. f. path. Anat. 212:391 ( (June 14) ) 1913. 14. Ghon, A., and Roman, B.: Ueber pseudoleukämische und leukämische Plasmazellen-Hyperplasie , Folia haemat. 15:72 ( (Feb. 27) ) 1913. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Otolaryngology American Medical Association

PLASMA CELL MYELOMA OF THE PHARYNX AND CERVICAL REGION WITHOUT SKELETAL INVOLVEMENT

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Publisher
American Medical Association
Copyright
Copyright © 1932 American Medical Association. All Rights Reserved.
ISSN
0003-9977
DOI
10.1001/archotol.1932.00630040057006
Publisher site
See Article on Publisher Site

Abstract

Abstract Multiple myeloma essentially represents a malignant neoplastic disease of the bone marrow which rarely, if ever, metastasizes. We are reporting a case of plasma cell myeloma of the pharynx and cervical region without apparent skeletal involvement. REPORT OF CASE A man, aged 60, came to the clinic on April 30, 1930. He had first noticed a swelling in his throat and in the right side of his neck two or three months previously. There was slight difficulty in swallowing and breathing but no pain. General examination gave essentially negative results, except for obesity, chronic myocardial degeneration and a moderate degree of hypertension. Examination of the throat revealed an ulcerated, polypoid mass about 3 by 2.5 cm. in the right side of the pharynx which apparently originated in the tonsil. There was also a mass in the right upper cervical region 4 cm. in diameter. Roentgenograms of the References 1. Ewing, James: Neoplastic Diseases , ed. 3, Philadelphia, W. B. Saunders Company, 1928, p. 321. 2. Jackson, Henry, Jr.; Parker, Frederic, Jr., and Bethea, J. M.: Studies of Diseases of the Lymphoid and Myeloid Tissues: II. Plasmatocytomata and Their Relation to Multiple Myelomata , Am. J. M. Sc. 181:169 ( (Feb.) ) 1931.Crossref 3. MacCallum, W. G.: A Text-Book of Pathology , ed. 4, Philadelphia, W. B. Saunders Company, 1928, p. 838. 4. Ribbert, Hugo: Ueber das Myelom , Centralbl. f. allg. Path. u. path. Anat. 15:337 ( (May 15) ) 1904. 5. Pepper, O. H. P., and Pearce, R. M.: Myeloma with Metastasis to Liver and Spleen , J. M. Research 37:171 ( (Sept.) ) 1917. 6. Meyerding, H. W.: Multiple Myeloma , Radiology 5:132 ( (Aug.) ) 1925. 7. Kolodny, Anatole: Bone Sarcoma , Surg., Gynec. & Obst. 44:155 and 162, 1927. 8. Geschickter, C. F., and Copeland, M. M.: Multiple Myeloma , Arch. Surg. 16:807 ( (April) ) 1928. 9. Schütz, Hans: Fall von multiplem Myelom mit Bence-Jones'scher Albuminurie und Metastase (beziehungsweise homologer autochthoner Neubildung) in der rechten Tonsille , Deutsches Arch. f. klin. Med. 113:441 ( (March 10) ) 1914. 10. Anders, J. M., and Boston, L. N.: Bence-Jones Albumosuria, with Report of Three Cases , Lancet 1:93 ( (Jan. 10) ) 1903. 11. Beck, J. C.: Some Uncommon Types of Neoplasms About the Head , Laryngoscope 40:511 ( (July) ) 1930. 12. Kaufmann, Eduard: Pathology , Philadelphia, P. Blakiston's Son & Co., 1929, vol. 1, pp. 272 and 625; vol. 2, pp. 1217 and 1221. 13. Kusunoki and Frank: Ueber ein plasmazelluläres Granulom unter dem klinischen Bilde von Lymphomen der Halslymphdrüsen und geschwulstartigen Knoten in der Nasenschleimhaut , Virchows Arch. f. path. Anat. 212:391 ( (June 14) ) 1913. 14. Ghon, A., and Roman, B.: Ueber pseudoleukämische und leukämische Plasmazellen-Hyperplasie , Folia haemat. 15:72 ( (Feb. 27) ) 1913.

Journal

Archives of OtolaryngologyAmerican Medical Association

Published: Jul 1, 1932

References