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Pilar Sheath Acanthoma

Pilar Sheath Acanthoma Abstract To the Editor.— Pilar sheath acanthoma, a type of follicular hamartoma, typically presents as an asymptomatic, small, solitary papule, often with a central opening, on the face (especially the upper lip) of adults. Recently, we have had the opportunity to review sections from eight such lesions, and have found several histologically constant features, including a widely dilated infundibulum plugged by cornified cells (Fig 1), numerous elongated epithelial aggregates emanating from the infundibular undersurface, and an inconspicuous fibrous stroma. In particular, the epithelial aggregates are characterized by the following: (1) many tiny keratinous cysts of two distinct types: (a) infundibular cysts ("epidermal" cyst-like), with flattened lining cells possessing prominent keratohyalin granules. We designate these infundibular because the lining cells of the normal follicular infundibulum possess these attributes. (b) isthmic cysts (Fig 2) ("trichilemmal" cystlike), whose lining cells are plump, with abundant, pale-staining cytoplasm, often devoid of keratohyalin granules. The appellation isthmic References 1. Plewig G: Sebaceous trichofolliculoma . J Cutan Pathol 1980;7:394-403.Crossref 2. Mehregan AH, Brownstein MH: Pilar sheath acanthoma . Arch Dermatol 1978;114:1495-1497.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

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Publisher
American Medical Association
Copyright
Copyright © 1987 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1987.01660290033010
Publisher site
See Article on Publisher Site

Abstract

Abstract To the Editor.— Pilar sheath acanthoma, a type of follicular hamartoma, typically presents as an asymptomatic, small, solitary papule, often with a central opening, on the face (especially the upper lip) of adults. Recently, we have had the opportunity to review sections from eight such lesions, and have found several histologically constant features, including a widely dilated infundibulum plugged by cornified cells (Fig 1), numerous elongated epithelial aggregates emanating from the infundibular undersurface, and an inconspicuous fibrous stroma. In particular, the epithelial aggregates are characterized by the following: (1) many tiny keratinous cysts of two distinct types: (a) infundibular cysts ("epidermal" cyst-like), with flattened lining cells possessing prominent keratohyalin granules. We designate these infundibular because the lining cells of the normal follicular infundibulum possess these attributes. (b) isthmic cysts (Fig 2) ("trichilemmal" cystlike), whose lining cells are plump, with abundant, pale-staining cytoplasm, often devoid of keratohyalin granules. The appellation isthmic References 1. Plewig G: Sebaceous trichofolliculoma . J Cutan Pathol 1980;7:394-403.Crossref 2. Mehregan AH, Brownstein MH: Pilar sheath acanthoma . Arch Dermatol 1978;114:1495-1497.Crossref

Journal

Archives of DermatologyAmerican Medical Association

Published: May 1, 1987

References