Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Picture of the Month

Picture of the Month Abstract Denouement and Discussion Tricho-Rhino-Phalangeal Syndrome Manifestations Major manifestations involve the hair, hands, and nose. The scalp hair is sparse, fine, and grows slowly. Sparcity of the hair may be particularly striking in the frontotemporal area, the pubis, axillae, and the lateral portions of the eyebrows. The nails are unusually thin. The most prominent feature of the face is a pear-shaped nose and increased nasolabial distance. Supernumerary incisors and small teeth have been described. Although height may be normal, many of the patients are below the 10th percentile. Characteristically, the hands have enlargement of the middle phalangeal joints with ulnar deviation of the fingers distally from that point. The distal phalanx of the thumb and large toe are often short; brachydactyly and pes planus may also be present. Other skeletal findings may include scoliosis, lordosis, Legg-Perthes disease, and winging of the scapulae. Some patients have an increased susceptibility to upper respiratory infections.Roentgenograms show cone-shaped epiphyses of References 1. Gorlin RJ, Cohen MM, Wolfson J: Tricho-rhino-phalangeal syndrome . Amer J Dis Child 118:595-599, 1969.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Diseases of Children American Medical Association

Loading next page...
 
/lp/american-medical-association/picture-of-the-month-JMJEzkhUdL
Publisher
American Medical Association
Copyright
Copyright © 1972 American Medical Association. All Rights Reserved.
ISSN
0002-922X
DOI
10.1001/archpedi.1972.02110130091014
Publisher site
See Article on Publisher Site

Abstract

Abstract Denouement and Discussion Tricho-Rhino-Phalangeal Syndrome Manifestations Major manifestations involve the hair, hands, and nose. The scalp hair is sparse, fine, and grows slowly. Sparcity of the hair may be particularly striking in the frontotemporal area, the pubis, axillae, and the lateral portions of the eyebrows. The nails are unusually thin. The most prominent feature of the face is a pear-shaped nose and increased nasolabial distance. Supernumerary incisors and small teeth have been described. Although height may be normal, many of the patients are below the 10th percentile. Characteristically, the hands have enlargement of the middle phalangeal joints with ulnar deviation of the fingers distally from that point. The distal phalanx of the thumb and large toe are often short; brachydactyly and pes planus may also be present. Other skeletal findings may include scoliosis, lordosis, Legg-Perthes disease, and winging of the scapulae. Some patients have an increased susceptibility to upper respiratory infections.Roentgenograms show cone-shaped epiphyses of References 1. Gorlin RJ, Cohen MM, Wolfson J: Tricho-rhino-phalangeal syndrome . Amer J Dis Child 118:595-599, 1969.Crossref

Journal

American Journal of Diseases of ChildrenAmerican Medical Association

Published: Jul 1, 1972

References