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PHYTOPHARMACOLOGIC TEST IN DERMATOLOGY: FURTHER STUDIES AND SOME CRITICAL ESTIMATIONS

PHYTOPHARMACOLOGIC TEST IN DERMATOLOGY: FURTHER STUDIES AND SOME CRITICAL ESTIMATIONS Abstract After five years' experience with the phytopharmacologic test, we believe that a third communication is in order for the purpose of a summary to date of results in pemphigus, and as a pertinent corollary to add some critical comments. Moreover, it gives opportune advantage to direct attention to certain other dermatoses which require elucidation. These conditions have come to our attention because apparently phytotoxic readings have been recorded sufficiently often to awaken more interest in dermatologic diagnosis and pathogenesis and perhaps in etiology. This is something of a compromise with our former communications, and is the result of a more comprehensive study. It will therefore be our purpose to discuss these findings in a general way, in order to place some evaluation on the possibilities of the test. In a previous communication we discussed the difficulties, the disadvantages and the pitfalls 1 of the technic, but we have also stressed References 1. Pels, I. R., and Macht, D. L.: Phytopharmacology of Pemphigus and Other Dermatoses: Additional Studies , Arch. Dermat. & Syph. 23:601 ( (April) ) 1931. 2. Brocq, L.: Ann. de dermat. et syph. 8:65, 1927. 3. Bertaccini, G.: Boll. d. Soc. ital. di biol. sper. 6:384, 1931. 4. Ambrogio, A.: Riun. Soc. ital. dermat. , Genoa, (October) , 1931. 5. Macht, D. L., and Livingston, M. B.: J. Gen. Physiol. 4:573, 1922. 6. Macht, D. L.: J. Pharmacol. & Exper. Therap. 29:461, 1926. 7. Some of these included normal readings (about 15 per cent). 8. Macht, D. I.: Proc. Soc. Exper. Biol. & Med. 27:150, 1929 9. Gilman, R. L.: The Senear-Usher Syndrome: A Dermatosis Combining the Features of Lupus Erythematosus and Pemphigus , Arch. Dermat. & Syph. 24:84 ( (July) ) 1931. 10. Woodburne, A. R.: Senear-Usher Pemphigus , Arch. Dermat. & Syph. 26:671 ( (Oct.) ) 1932. 11. Taussig, L.: The Senear-Usher Syndrome: A Variety of Lupus Erythematosus , Arch. Dermat. & Syph. 27:498 ( (March) ) 1933. 12. Ludy, J. B., and Devalin, C. M.: Urol. & Cutan. Rev. 36:817, 1932. 13. Macht, D. I.: Proc. Nat. Acad. Sc., to be published. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology and Syphilology American Medical Association

PHYTOPHARMACOLOGIC TEST IN DERMATOLOGY: FURTHER STUDIES AND SOME CRITICAL ESTIMATIONS

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Publisher
American Medical Association
Copyright
Copyright © 1934 American Medical Association. All Rights Reserved.
ISSN
0096-6029
DOI
10.1001/archderm.1934.01460080036003
Publisher site
See Article on Publisher Site

Abstract

Abstract After five years' experience with the phytopharmacologic test, we believe that a third communication is in order for the purpose of a summary to date of results in pemphigus, and as a pertinent corollary to add some critical comments. Moreover, it gives opportune advantage to direct attention to certain other dermatoses which require elucidation. These conditions have come to our attention because apparently phytotoxic readings have been recorded sufficiently often to awaken more interest in dermatologic diagnosis and pathogenesis and perhaps in etiology. This is something of a compromise with our former communications, and is the result of a more comprehensive study. It will therefore be our purpose to discuss these findings in a general way, in order to place some evaluation on the possibilities of the test. In a previous communication we discussed the difficulties, the disadvantages and the pitfalls 1 of the technic, but we have also stressed References 1. Pels, I. R., and Macht, D. L.: Phytopharmacology of Pemphigus and Other Dermatoses: Additional Studies , Arch. Dermat. & Syph. 23:601 ( (April) ) 1931. 2. Brocq, L.: Ann. de dermat. et syph. 8:65, 1927. 3. Bertaccini, G.: Boll. d. Soc. ital. di biol. sper. 6:384, 1931. 4. Ambrogio, A.: Riun. Soc. ital. dermat. , Genoa, (October) , 1931. 5. Macht, D. L., and Livingston, M. B.: J. Gen. Physiol. 4:573, 1922. 6. Macht, D. L.: J. Pharmacol. & Exper. Therap. 29:461, 1926. 7. Some of these included normal readings (about 15 per cent). 8. Macht, D. I.: Proc. Soc. Exper. Biol. & Med. 27:150, 1929 9. Gilman, R. L.: The Senear-Usher Syndrome: A Dermatosis Combining the Features of Lupus Erythematosus and Pemphigus , Arch. Dermat. & Syph. 24:84 ( (July) ) 1931. 10. Woodburne, A. R.: Senear-Usher Pemphigus , Arch. Dermat. & Syph. 26:671 ( (Oct.) ) 1932. 11. Taussig, L.: The Senear-Usher Syndrome: A Variety of Lupus Erythematosus , Arch. Dermat. & Syph. 27:498 ( (March) ) 1933. 12. Ludy, J. B., and Devalin, C. M.: Urol. & Cutan. Rev. 36:817, 1932. 13. Macht, D. I.: Proc. Nat. Acad. Sc., to be published.

Journal

Archives of Dermatology and SyphilologyAmerican Medical Association

Published: Feb 1, 1934

References