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PHYSIOLOGIC OBSERVATIONS ON A PATIENT WITH AN EXTERNAL PANCREATIC FISTULA

PHYSIOLOGIC OBSERVATIONS ON A PATIENT WITH AN EXTERNAL PANCREATIC FISTULA Abstract THE FUNDAMENTAL information about external pancreatic secretion has been derived in the main from experimental studies on animals, although an occasional report is found in the medical literature about physiologic observations made on human subjects. Opportunity was afforded Wiper and one of us (J. M. M.)1 to study three persons with external pancreatic fistula, and the results of these investigations have been published. A further chance was given to us to repeat and enlarge on the investigations made previously. An external pancreatic fistula developed subsequent to a surgical procedure for a congenital duplication of the stomach in a 32 year old white man, the subject of this study. The duplication was removed by doing a partial gastrectomy. In the interpretation of the results which are concerned with the usually accepted theory of stimulation of pancreatic secretion, it should be remembered that a large part of the distal portion of References 1. Miller, J. M., and Wiper, T. B.: Physiologic Observations on Patients with External Pancreatic Fistula , Ann. Surg. 6:852-872 ( (Dec.) ) 1944.Crossref 2. McCaughan, J. M.; Sinner, B. L., and Sullivan, C. J.: The External Secretory Function of the Human Pancreas: Physiologic Observations , Arch. Int. Med. 61:739-754 ( (May) ) 1938.Crossref 3. Komarov, S. A.; Langstroth, G. O., and McRae, D. R.: Secretion of Crystalloids and Protein Material by Pancreas in Response to Secretin Administration , Canad. J. Research 17:113-123 ( (May) ) 1939.Crossref 4. Hart, W. M., and Thomas, J. E.: Bicarbonate and Chloride of Pancreatic Juice Secreted in Response to Various Stimuli , Gastroenterology 4:409-420 ( (May) ) 1945. 5. Gamble, J. L.: Physiology and Pathology of Extracellular Fluid , in Chemical Anatomy , Cambridge, Mass., Harvard Medical School, 1942. 6. Goodman, L., and Gilman, A.: The Pharmacological Basis of Therapeutics , New York, The Macmillan Company, 1941. 7. Coffey, R. J.; Koppanyi, T., and Linegar, C. R.: The Effect of Barbiturates on Digestive Secretion , Am. J. Digest. Dis. 7:21-23 ( (Jan.) ) 1940.Crossref 8. Comfort, M. W., and Priestley, J. T.: External Pancreatic Fistula: Report of a Case with Physiologic Observations and Surgical Considerations , Proc. Staff Meet. Mayo Clin. 18:409-416 ( (Nov. 3) ) 1943. 9. Wiper, T. B., and Miller, J. M.: Surgical Aspects of Pancreatic Fistula , Ann. Surg. 120:52-59 ( (July) ) 1944.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Surgery American Medical Association

PHYSIOLOGIC OBSERVATIONS ON A PATIENT WITH AN EXTERNAL PANCREATIC FISTULA

Archives of Surgery , Volume 61 (2) – Aug 1, 1950

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Publisher
American Medical Association
Copyright
Copyright © 1950 American Medical Association. All Rights Reserved.
ISSN
0004-0010
eISSN
1538-3644
DOI
10.1001/archsurg.1950.01250020350016
Publisher site
See Article on Publisher Site

Abstract

Abstract THE FUNDAMENTAL information about external pancreatic secretion has been derived in the main from experimental studies on animals, although an occasional report is found in the medical literature about physiologic observations made on human subjects. Opportunity was afforded Wiper and one of us (J. M. M.)1 to study three persons with external pancreatic fistula, and the results of these investigations have been published. A further chance was given to us to repeat and enlarge on the investigations made previously. An external pancreatic fistula developed subsequent to a surgical procedure for a congenital duplication of the stomach in a 32 year old white man, the subject of this study. The duplication was removed by doing a partial gastrectomy. In the interpretation of the results which are concerned with the usually accepted theory of stimulation of pancreatic secretion, it should be remembered that a large part of the distal portion of References 1. Miller, J. M., and Wiper, T. B.: Physiologic Observations on Patients with External Pancreatic Fistula , Ann. Surg. 6:852-872 ( (Dec.) ) 1944.Crossref 2. McCaughan, J. M.; Sinner, B. L., and Sullivan, C. J.: The External Secretory Function of the Human Pancreas: Physiologic Observations , Arch. Int. Med. 61:739-754 ( (May) ) 1938.Crossref 3. Komarov, S. A.; Langstroth, G. O., and McRae, D. R.: Secretion of Crystalloids and Protein Material by Pancreas in Response to Secretin Administration , Canad. J. Research 17:113-123 ( (May) ) 1939.Crossref 4. Hart, W. M., and Thomas, J. E.: Bicarbonate and Chloride of Pancreatic Juice Secreted in Response to Various Stimuli , Gastroenterology 4:409-420 ( (May) ) 1945. 5. Gamble, J. L.: Physiology and Pathology of Extracellular Fluid , in Chemical Anatomy , Cambridge, Mass., Harvard Medical School, 1942. 6. Goodman, L., and Gilman, A.: The Pharmacological Basis of Therapeutics , New York, The Macmillan Company, 1941. 7. Coffey, R. J.; Koppanyi, T., and Linegar, C. R.: The Effect of Barbiturates on Digestive Secretion , Am. J. Digest. Dis. 7:21-23 ( (Jan.) ) 1940.Crossref 8. Comfort, M. W., and Priestley, J. T.: External Pancreatic Fistula: Report of a Case with Physiologic Observations and Surgical Considerations , Proc. Staff Meet. Mayo Clin. 18:409-416 ( (Nov. 3) ) 1943. 9. Wiper, T. B., and Miller, J. M.: Surgical Aspects of Pancreatic Fistula , Ann. Surg. 120:52-59 ( (July) ) 1944.Crossref

Journal

Archives of SurgeryAmerican Medical Association

Published: Aug 1, 1950

References