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Abstract GENERALLY speaking, the physical allergies deal with those reactions of hypersensitiveness due to cold, heat, radiant energy, pressure, and mechanical stimuli. I am particularly concerned in this study with those reactions due to heat and cold. However, before going on to my subject I should like to mention that reactions of hypersensitiveness occur occasionally with roentgen, grenz, and radium irradiation, in addition to the rays of the visible spectrum, and it is important to note that certain instances of so-called photosensitivity really are due to the heat of such energy rather than the light per se. If we are to accept the reactions of hypersensitiveness to heat and cold as truly allergic we must use the term broadly and in the sense originally defined by von Pirquet, that is, as an "altered capacity to react." Almost no one, however, agrees with this broad concept, but the feeling persists that the References 1. Rajka, E., and Asboth, A.: Cold Urticaria: Investigations Concerning Its Pathogenesis , Ann. Allergy 9:642-652 ( (Sept.) -Oct.) 1951. 2. Rajka and Asboth.1 3. Rothman, S., in discussion on Rodin, H. H.: Sensitivity to Cold , A. M. A. Arch. Dermat. & Syph. 63:155 ( (Jan.) ) 1951. 4. Urbach, E.; Herrman, M. F., and Gottlieb, P. M.: Cold Allergy and Cold Pathergy , A. M. A. Arch. Dermat. & Syph. 43:366-374 ( (Feb.) ) 1941. 5. Urbach, E., and Gottlieb, P. M.: Allergy , Ed. 2, New York, Grune & Stratton, Inc., 1946, Chap. 17 , pp. 409-434. 6. Melczer, N., and Wlassics, T.: Über die Wärmeüberempfindlichkeit , Arch. Dermat. u. Syph. 176:157-166 ( (Oct.) ) 1937. 7. Rostenberg, A., Jr., in discussion on Rodin, H. H.: Sensitivity to Cold , A. M. A. Arch. Dermat. & Syph. 63:154 ( (Jan.) ) 1951. 8. The 1951 Year Book of Dermatology and Syphilology , edited by M. B. Sulzberger, and R. L. Baer, Chicago, The Year Book Publishers, Inc., 1951, pp. 182-186. 9. Duke, W. W.: Urticaria Caused Specifically by the Action of Physical Agents (Light, Cold, Heat, Freezing, Burns, Mechanical Irritation, and Physical and Mental Exertion) , J. A. M. A. 83:3-8 ( (July 5) ) 1924. 10. Peters, G. A., and Silverman, J. J.: Role of Histamine and Acetylcholine in the Mechanism of Heat Allergy: Report of Studies on a Soldier , Arch. Int. Med. 77:526-543 ( (May) ) 1946. 11. Melczer and Wlassics.2e 12. Peters and Silverman.6 13. Nomland, R.: Cholinogenic Urticaria and Cholinogenic Itching , Arch. Dermat. & Syph. 50:247-249 ( (Oct.) ) 1944. 14. Hopkins, J. G.; Kesten, B. M., and Hazel, O. G.: Urticaria Provoked by Heat or by Psychic Stimuli , Arch. Dermat. & Syph. 38:679-691 ( (Nov.) ) 1938. 15. Grant, R. T.; Pearson, R. S. B., and Comeau, W. J.: Observations on Urticaria Provoked by Emotion, by Exercise and by Warming the Body , Clin. Sc. 2:253-272 ( (July) ) 1936. 16. Sigel, H.: Urticaria Caused by Heat, Exertion and Excitement: Report on 22 Cases Among American Soldiers in Japan , Arch. Dermat. & Syph. 57:204-209 ( (Feb.) ) 1948. 17. Horton, B. T.: Cold Allergy: Report of 2 Cases , Proc. Staff Meet., Mayo Clin. 2:276-278 ( (Nov. 23) ) 1927. 18. Horton, B. T.; Brown, G. E., and Roth, G. M.: Hypersensitiveness to Cold, with Local and Systemic Manifestations of a Histamine-Like Character: Its Amenability to Treatment , J. A. M. A. 107:1263-1269 ( (Oct. 17) ) 1936. 19. Williams, H. L.: The Syndrome of Physical or Intrinsic Allergy of the Head: Myalgia of the Head (Sinus Headache) , Proc. Staff Meet., Mayo Clin. 20:177-183 ( (June 13) ) 1945. 20. Urbach and co-workers.2c,d 21. Rodin, H. H.: Sensitivity to Cold , A. M. A. Arch. Dermat. & Syph. 63:152-154 ( (Jan.) ) 1951. 22. Witherspoon, F. G.; White, C. B.; Bazemore, J. M., and Hailey, H.: Familial Urticaria Due to Cold , A. M. A. Arch. Dermat. & Syph. 58:52-55 ( (July) ) 1948. 23. Kile, R. L., and Rusk, H. A.: A Case of Cold Urticaria with an Unusual Family History , J. A. M. A. 114:1067-1068 ( (March 23) ) 1940. 24. Rasmussen, K. A.: The Effect of Antihistaminics on Histamine Whealing and on Dermographism: Elucidated by Comparative Electrophoretical Experiments , Acta dermat.-venereol. 29:564-571, 1949. 25. Kalz, F.; Bower, C. M., and Prichard, H.: Delayed and Persistent Dermographia , Arch. Dermat. & Syph. 61:772-780 ( (May) ) 1950. 26. Sherman, W. B., and Seebohm, P. M.: Passive Transfer of Cold Urticaria , J. Allergy 21:414-424 ( (Sept.) ) 1950. 27. Williams, H. L.: A Concept of Allergy as Autonomic Dysfunction Suggested as an Improved Working Hypothesis , Tr. Am. Acad. Ophth. 55:123-146 ( (Nov.) -Dec.) 1951.
A.M.A. Archives of Dermatology & Syphilology – American Medical Association
Published: Jul 1, 1953
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