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Physical Activity and Risk of Breast Cancer Among Postmenopausal Women

Physical Activity and Risk of Breast Cancer Among Postmenopausal Women ORIGINAL INVESTIGATION Physical Activity and Risk of Breast Cancer Among Postmenopausal Women A. Heather Eliassen, ScD; Susan E. Hankinson, RN, ScD; Bernard Rosner, PhD; Michelle D. Holmes, MD, DrPH; Walter C. Willett, MD, DrPH Background: Physical activity has many health ben- 0.93; P.001 for trend). Compared with women who efits. Although greater activity has been related to lower were least active at menopause and through follow-up postmenopausal breast cancer risk, important details re- (9 MET-h/wk [approximately 30 minutes of walking main unclear, including type, intensity, and timing of ac- at an average pace on most days of the week]), women tivity and whether the association varies by subgroups. who increased activity were at lower risk (9 MET- h/wk at menopause and 9 MET-h/wk during follow- Methods: Within the prospective Nurses’ Health Study, up: HR, 0.90; 95% CI, 0.82-0.98). Among specific ac- we assessed the associations of specific and total activ- tivities modeled simultaneously, brisk walking was ity, queried every 2 to 4 years since 1986, with breast can- associated with lower risk (per 20 MET-h/wk [5 h/wk]: cer risk. Cox proportional hazards models were used to HR, 0.91; 95% CI, 0.84-0.98). The association with total calculate hazard ratios (HRs) http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Internal Medicine American Medical Association

Physical Activity and Risk of Breast Cancer Among Postmenopausal Women

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References (34)

Publisher
American Medical Association
Copyright
Copyright 2010 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6106
eISSN
2168-6114
DOI
10.1001/archinternmed.2010.363
pmid
20975025
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL INVESTIGATION Physical Activity and Risk of Breast Cancer Among Postmenopausal Women A. Heather Eliassen, ScD; Susan E. Hankinson, RN, ScD; Bernard Rosner, PhD; Michelle D. Holmes, MD, DrPH; Walter C. Willett, MD, DrPH Background: Physical activity has many health ben- 0.93; P.001 for trend). Compared with women who efits. Although greater activity has been related to lower were least active at menopause and through follow-up postmenopausal breast cancer risk, important details re- (9 MET-h/wk [approximately 30 minutes of walking main unclear, including type, intensity, and timing of ac- at an average pace on most days of the week]), women tivity and whether the association varies by subgroups. who increased activity were at lower risk (9 MET- h/wk at menopause and 9 MET-h/wk during follow- Methods: Within the prospective Nurses’ Health Study, up: HR, 0.90; 95% CI, 0.82-0.98). Among specific ac- we assessed the associations of specific and total activ- tivities modeled simultaneously, brisk walking was ity, queried every 2 to 4 years since 1986, with breast can- associated with lower risk (per 20 MET-h/wk [5 h/wk]: cer risk. Cox proportional hazards models were used to HR, 0.91; 95% CI, 0.84-0.98). The association with total calculate hazard ratios (HRs)

Journal

JAMA Internal MedicineAmerican Medical Association

Published: Oct 25, 2010

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