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PHS Provides Immunoglobulin

PHS Provides Immunoglobulin The 6000 officers of the US Public Health Service (PHS) Commissioned Corps are being asked to volunteer for smallpox vaccine inoculation to help increase the nation's supply of vaccinia immunoglobulin. Collected via plasmapheresis 7 to 10 days after immunization, vaccinia immunoglobulin is used to counteract adverse effects of smallpox vaccination. In late October, the office of the US Surgeon General sent a letter to all officers requesting their help: "It is possible that our national security may require a large-scale smallpox vaccination program. Smallpox vaccination can result in adverse reactions in some recipients. Individuals who have never previously been immunized against smallpox, especially those with a weakened immune system or with certain skin disorders, face an increased risk of serious adverse events (including death) when they receive the smallpox vaccination. Vaccinia immunoglobulin (VIG), which is prepared from plasma from individuals immunized against smallpox, can help treat these adverse reactions." The Centers for Disease Control and Prevention began the immunoglobulin collection program earlier this fall, and by late October had collected antibodies from about 1000 employees. Only PHS officers who have previously received smallpox vaccine are eligible for the program, as previous exposure to the vaccinia virus reduces the risk of adverse effects. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

PHS Provides Immunoglobulin

JAMA , Volume 288 (19) – Nov 20, 2002

PHS Provides Immunoglobulin

Abstract

The 6000 officers of the US Public Health Service (PHS) Commissioned Corps are being asked to volunteer for smallpox vaccine inoculation to help increase the nation's supply of vaccinia immunoglobulin. Collected via plasmapheresis 7 to 10 days after immunization, vaccinia immunoglobulin is used to counteract adverse effects of smallpox vaccination. In late October, the office of the US Surgeon General sent a letter to all officers requesting their help: "It is possible that our...
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Publisher
American Medical Association
Copyright
Copyright © 2002 American Medical Association. All Rights Reserved.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.288.19.2397
Publisher site
See Article on Publisher Site

Abstract

The 6000 officers of the US Public Health Service (PHS) Commissioned Corps are being asked to volunteer for smallpox vaccine inoculation to help increase the nation's supply of vaccinia immunoglobulin. Collected via plasmapheresis 7 to 10 days after immunization, vaccinia immunoglobulin is used to counteract adverse effects of smallpox vaccination. In late October, the office of the US Surgeon General sent a letter to all officers requesting their help: "It is possible that our national security may require a large-scale smallpox vaccination program. Smallpox vaccination can result in adverse reactions in some recipients. Individuals who have never previously been immunized against smallpox, especially those with a weakened immune system or with certain skin disorders, face an increased risk of serious adverse events (including death) when they receive the smallpox vaccination. Vaccinia immunoglobulin (VIG), which is prepared from plasma from individuals immunized against smallpox, can help treat these adverse reactions." The Centers for Disease Control and Prevention began the immunoglobulin collection program earlier this fall, and by late October had collected antibodies from about 1000 employees. Only PHS officers who have previously received smallpox vaccine are eligible for the program, as previous exposure to the vaccinia virus reduces the risk of adverse effects.

Journal

JAMAAmerican Medical Association

Published: Nov 20, 2002

Keywords: immunoglobulins

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