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Persistent Denudation of the Scalp in Cicatricial Pemphigoid: Treatment by Skin Grafting

Persistent Denudation of the Scalp in Cicatricial Pemphigoid: Treatment by Skin Grafting Abstract Two unusual, striking, and puzzling cases of persistent denudation of the scalp have been followed for 5 and 10 years respectively by 2 of us (A. H. S. and J. W. B.). The first patient was presented before the Chicago Dermatological Society in February, 1955, as: "A Case for Diagnosis— Pemphigus Vulgaris?"1 This led to the comparative study of the second such extraordinary clinical manifestation. The diagnosis of pemphigus is often made only after enough time has elapsed to complete the characteristic picture. Senear2 has pointed out the effectiveness of certain well-accepted criteria for diagnosis in certain cases. When the disorders of the pemphigoid group are added to the differential problem, however, the dilemma becomes compounded. The present report concerns 2 cases of cicatricial pemphigoid. Both patients displayed massive nonhealing erosive lesions affecting the major portions of the scalp. Report of Cases Case 1.— A 56-year-old white woman References 1. Slepyan, A. H.: Case for Diagnosis: (Pemphigus Vulgaris?) , A.M.A. Arch. Derm. 72: 77, 1955.Crossref 2. Senear, F. E.: Chronic Pemphigus Vulgaris , A.M.A. Arch. Derm. Syph. 65:429, 1952.Crossref 3. Fisher, I.: Pemphigus Vulgaris: A Correlation of Clinical and Microscopic Observations , A.M.A. Arch. Derm. 74:50, 1956.Crossref 4. Prakken, J. R., and Woerdeman, M. J.: Pemphigoid (Para Pemphigus): Its Relationship to Other Bullous Dermatoses , Brit. J. Derm. 67: 92, 1955.Crossref 5. Director, W.: Pemphigus Vulgaris: A Clinicopathologic Study , A.M.A. Arch. Derm. Syph. 65: 155, 1952.Crossref 6. Goldschlag, F.: Pemphigus , Aust. J. Derm. 2:65, 1955.Crossref 7. Jablonska, S.; Segal, P.; Milewski, B., and Dabrowska, H.: Pemphigoid Mucosae , Acta Dermatovener. 37:364, 1957. 8. Lever, W.: Personal communication to the authors. 9. Lever, W. F.: Pemphigus , Medicine (Balt.) 32:1, 1953.Crossref 10. Brennan, J. G., and Montgomery, H.: Pemphigus and Other Bullous Dermatoses: Correlation of Clinical and Pathological Findings , J. Invest. Derm. 21:349, 1953.Crossref 11. Lodin, A., and Gentele, H.: Benign Mucous Membrane Pemphigoid (Pemphigus Conjunctivae) , Acta Dermatovener. 37:357, 1957. 12. Brunsting, L. A., and Perry, H. O.: Benign Pemphigoid? A Report of 7 Cases with Chronic, Scarring, Herpetiform Plaques About the Head and Neck , A.M.A. Arch. Derm. 75:489, 1957.Crossref 13. Sneddon, I. B., and Church, R.: Diagnosis and Treatment of Pemphigoid: A Report on 22 Cases , Brit. Med. J. 2:1360, 1955.Crossref 14. Ziprkowski, L.; Krakrowski, A., and Bornstein, L. A.: Pemphigus Vulgaris and Skin Grafting , J. Invest. Derm. 34:285, 1960. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Persistent Denudation of the Scalp in Cicatricial Pemphigoid: Treatment by Skin Grafting

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Publisher
American Medical Association
Copyright
Copyright © 1961 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1961.01580150090015
Publisher site
See Article on Publisher Site

Abstract

Abstract Two unusual, striking, and puzzling cases of persistent denudation of the scalp have been followed for 5 and 10 years respectively by 2 of us (A. H. S. and J. W. B.). The first patient was presented before the Chicago Dermatological Society in February, 1955, as: "A Case for Diagnosis— Pemphigus Vulgaris?"1 This led to the comparative study of the second such extraordinary clinical manifestation. The diagnosis of pemphigus is often made only after enough time has elapsed to complete the characteristic picture. Senear2 has pointed out the effectiveness of certain well-accepted criteria for diagnosis in certain cases. When the disorders of the pemphigoid group are added to the differential problem, however, the dilemma becomes compounded. The present report concerns 2 cases of cicatricial pemphigoid. Both patients displayed massive nonhealing erosive lesions affecting the major portions of the scalp. Report of Cases Case 1.— A 56-year-old white woman References 1. Slepyan, A. H.: Case for Diagnosis: (Pemphigus Vulgaris?) , A.M.A. Arch. Derm. 72: 77, 1955.Crossref 2. Senear, F. E.: Chronic Pemphigus Vulgaris , A.M.A. Arch. Derm. Syph. 65:429, 1952.Crossref 3. Fisher, I.: Pemphigus Vulgaris: A Correlation of Clinical and Microscopic Observations , A.M.A. Arch. Derm. 74:50, 1956.Crossref 4. Prakken, J. R., and Woerdeman, M. J.: Pemphigoid (Para Pemphigus): Its Relationship to Other Bullous Dermatoses , Brit. J. Derm. 67: 92, 1955.Crossref 5. Director, W.: Pemphigus Vulgaris: A Clinicopathologic Study , A.M.A. Arch. Derm. Syph. 65: 155, 1952.Crossref 6. Goldschlag, F.: Pemphigus , Aust. J. Derm. 2:65, 1955.Crossref 7. Jablonska, S.; Segal, P.; Milewski, B., and Dabrowska, H.: Pemphigoid Mucosae , Acta Dermatovener. 37:364, 1957. 8. Lever, W.: Personal communication to the authors. 9. Lever, W. F.: Pemphigus , Medicine (Balt.) 32:1, 1953.Crossref 10. Brennan, J. G., and Montgomery, H.: Pemphigus and Other Bullous Dermatoses: Correlation of Clinical and Pathological Findings , J. Invest. Derm. 21:349, 1953.Crossref 11. Lodin, A., and Gentele, H.: Benign Mucous Membrane Pemphigoid (Pemphigus Conjunctivae) , Acta Dermatovener. 37:357, 1957. 12. Brunsting, L. A., and Perry, H. O.: Benign Pemphigoid? A Report of 7 Cases with Chronic, Scarring, Herpetiform Plaques About the Head and Neck , A.M.A. Arch. Derm. 75:489, 1957.Crossref 13. Sneddon, I. B., and Church, R.: Diagnosis and Treatment of Pemphigoid: A Report on 22 Cases , Brit. Med. J. 2:1360, 1955.Crossref 14. Ziprkowski, L.; Krakrowski, A., and Bornstein, L. A.: Pemphigus Vulgaris and Skin Grafting , J. Invest. Derm. 34:285, 1960.

Journal

Archives of DermatologyAmerican Medical Association

Published: Sep 1, 1961

References