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EPIDEMIOLOGY SECTION EDITOR: LESLIE HYMAN, PhD The Singapore Malay Eye Study V. Swetha E. Jeganathan, MD; Tien Yin Wong, FRCS, PhD; Paul J. Foster, FRCS, PhD; Jonathan G. Crowston, PhD, FRCOphth; Wan Ting Tay, BSC; Su Chi Lim, MD; Seang-Mei Saw, PhD; E. Shyong Tai, MCRP; Tin Aung, MBBS, PhD, FRCS(Edin) Objective: To examine the relationship between pe- intraocular pressure (age- and sex-adjusted mean, 16.4 ripheral artery disease (PAD) and glaucoma. vs 15.5; P=.05), and a larger vertical cup-disc ratio (age- and sex-adjusted mean, 0.45 vs 0.40; P=.02). The asso- Methods: As part of a population-based study of 3280 ciation of PAD with glaucoma persisted while control- persons of Malay descent (78.7% response) aged 40 to ling for hypertension, diabetes, body mass index, serum 80 years examined between August 1, 2004, and June 30, triglyceride levels, and -blocker use (multivariable- 2006, the ankle-brachial index (ABI) was assessed in all adjusted OR, 2.55; 95% CI, 1.09-5.98) and was stronger persons with known diabetes mellitus and every fifth sys- in people with diabetes (multivariable-adjusted OR, 2.91; tematically sampled participant without diabetes. Pe- 95% CI, 1.14-7.44). ripheral artery disease was deemed present if the ABI was 0.9 or less. Glaucoma was diagnosed
JAMA Ophthalmology – American Medical Association
Published: Jul 1, 2009
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